Stoking the drug target pipeline for human African trypanosomiasis

Por Phillips, Margaret A.
Publicado em 2012

Regulated Expression of an Essential Allosteric Activator of Polyamine Biosynthesis in African Trypanosomes

Por Willert, Erin K., Phillips, Margaret A.
Publicado em 2008

Cross-species activation of trypanosome S-adenosylmethionine decarboxylase by the regulatory subunit prozyme

Por Willert, Erin K., Phillips, Margaret A.
Publicado em 2009

Plasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy

Por Phillips, Margaret A., Rathod, Pradipsinh K.
Publicado em 2010

A Gateway® compatible vector for gene silencing in bloodstream form Trypanosoma brucei

Por Kalidas, Savitha, Li, Qiong, Phillips, Margaret A
Publicado em 2011

State of the Art in African Trypanosome Drug Discovery

Por Jacobs, Robert T., Nare, Bakela, Phillips, Margaret A.
Publicado em 2011

Genetic Validation of Trypanosoma brucei Glutathione Synthetase as an Essential Enzyme

Por Pratt, Chelsea, Nguyen, Suong, Phillips, Margaret A.
Publicado em 2014

Allosteric regulation of an essential trypanosome polyamine biosynthetic enzyme by a catalytically dead homolog

Por Willert, Erin K., Fitzpatrick, Richard, Phillips, Margaret A.
Publicado em 2007

Trypanosoma brucei S-Adenosylmethionine Decarboxylase N Terminus Is Essential for Allosteric Activation by the Regulatory Subunit Prozyme

Por Velez, Nahir, Brautigam, Chad A., Phillips, Margaret A.
Publicado em 2013

Phosphatidylinositol 4-Kinase III-β Is Required for Golgi Maintenance and Cytokinesis in Trypanosoma brucei

Por Rodgers, Melissa J., Albanesi, Joseph P., Phillips, Margaret A.
Publicado em 2007

RNA Interference-Mediated Silencing of Ornithine Decarboxylase and Spermidine Synthase Genes in Trypanosoma brucei Provides Insight into Regulation of Polyamine Biosynthesis

Por Xiao, Yanjing, McCloskey, Diane E., Phillips, Margaret A.
Publicado em 2009

Targeted Nanodelivery of Drugs and Diagnostics

Por Phillips, Margaret A., Gran, Martin L., Peppas, Nicholas A.
Publicado em 2010

CELLULAR EVALUATION OF SYNTHESIZED INSULIN/TRANSFERRIN BIOCONJUGATES FOR ORAL INSULIN DELIVERY USING INTELLIGENT COMPLEXATION HYDROGELS

Por Shofner, Justin P., Phillips, Margaret A., Peppas, Nicholas A.
Publicado em 2010

The X-ray structure of Paramecium bursaria Chlorella virus arginine decarboxylase: insight into the structural basis for substrate specificity

Por Shah, Rahul, Akella, Radha, Goldsmith, Elizabeth J., Phillips, Margaret A.
Publicado em 2007

The X-ray structure of Plasmodium falciparum dihydroorotate dehydrogenase bound to a potent and selective N-phenylbenzamide inhibitor reveals novel binding-site interactions

Por Deng, Xiaoyi, Matthews, David, Rathod, Pradipsinh K., Phillips, Margaret A.
Publicado no Acta Crystallogr F Struct Biol Commun (2015)

Analysis of Flavin Oxidation and Electron Transfer Inhibition in Plasmodium falciparum Dihydroorotate Dehydrogenase

Por Malmquist, Nicholas A., Gujjar, Ramesh, Rathod, Pradipsinh K., Phillips, Margaret A.
Publicado em 2008

Atovaquone Tolerance in Plasmodium falciparum Parasites Selected for High-Level Resistance to a Dihydroorotate Dehydrogenase Inhibitor

Por Guler, Jennifer L., White, John, Phillips, Margaret A., Rathod, Pradipsinh K.
Publicado no Antimicrob Agents Chemother (2014)

Allosteric Activation of Trypanosomatid Deoxyhypusine Synthase by a Catalytically Dead Paralog

Por Nguyen, Suong, Jones, Deuan C., Wyllie, Susan, Fairlamb, Alan H., Phillips, Margaret A.
Publicado em 2013

A Multiple Aminoacyl-tRNA Synthetase Complex That Enhances tRNA-Aminoacylation in African Trypanosomes

Por Cestari, Igor, Kalidas, Savitha, Monnerat, Severine, Anupama, Atashi, Phillips, Margaret A., Stuart, Kenneth
Publicado em 2013

Discovery of Potent and Selective Inhibitors of Trypanosoma brucei Ornithine Decarboxylase

Por Smithson, David C., Lee, Jeongmi, Shelat, Anang A., Phillips, Margaret A., Guy, R. Kiplin
Publicado em 2010