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Discovery of Potent and Selective Inhibitors of Trypanosoma brucei Ornithine Decarboxylase
Human African trypanosomiasis, caused by the eukaryotic parasite Trypanosoma brucei, is a serious health problem in much of central Africa. The only validated molecular target for treatment of human African trypanosomiasis is ornithine decarboxylase (ODC), which catalyzes the first step in polyamine...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878083/ https://ncbi.nlm.nih.gov/pubmed/20220141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.081588 |
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