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Discovery of Potent and Selective Inhibitors of Trypanosoma brucei Ornithine Decarboxylase
Human African trypanosomiasis, caused by the eukaryotic parasite Trypanosoma brucei, is a serious health problem in much of central Africa. The only validated molecular target for treatment of human African trypanosomiasis is ornithine decarboxylase (ODC), which catalyzes the first step in polyamine...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878083/ https://ncbi.nlm.nih.gov/pubmed/20220141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.081588 |
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