An in vitro ADME and in vivo Pharmacokinetic Study of Novel TB-Active Decoquinate Derivatives

af Tanner, Lloyd, Haynes, Richard K., Wiesner, Lubbe
Udgivet i Front Pharmacol (2019)

Accumulation of TB-Active Compounds in Murine Organs Relevant to Infection by Mycobacterium tuberculosis

af Tanner, Lloyd, Haynes, Richard K., Wiesner, Lubbe
Udgivet i Front Pharmacol (2020)

Neurotoxic Mode of Action of Artemisinin

af Schmuck, Gabriele, Roehrdanz, Elke, Haynes, Richard K., Kahl, Regine
Udgivet 2002

Artemisinins: their growing importance in medicine

af Krishna, Sanjeev, Bustamante, Leyla, Haynes, Richard K., Staines, Henry M.
Udgivet 2008

Artemisinins Inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense In Vitro Growth

af Mishina, Yuliya V., Krishna, Sanjeev, Haynes, Richard K., Meade, John C.
Udgivet 2007

Artemisone and Artemiside Control Acute and Reactivated Toxoplasmosis in a Murine Model

af Dunay, Ildiko R., Chan, Wing Chi, Haynes, Richard K., Sibley, L. David
Udgivet 2009

Artemisinin Antimalarials Do Not Inhibit Hemozoin Formation

af Haynes, Richard K., Monti, Diego, Taramelli, Donatella, Basilico, Nicoletta, Parapini, Silvia, Olliaro, Piero
Udgivet 2003

Recent progress in the development of anti-malarial quinolones

af Beteck, Richard M, Smit, Frans J, Haynes, Richard K, N’Da, David D
Udgivet 2014

Assessment of the Induction of Dormant Ring Stages in Plasmodium falciparum Parasites by Artemisone and Artemisone Entrapped in Pheroid Vesicles In Vitro

af Grobler, Lizette, Chavchich, Marina, Haynes, Richard K., Edstein, Michael D., Grobler, Anne F.
Udgivet i Antimicrob Agents Chemother (2014)

Re-evaluation of how artemisinins work in light of emerging evidence of in vitro resistance

af Krishna, Sanjeev, Woodrow, Charles J., Staines, Henry M., Haynes, Richard K., Mercereau-Puijalon, Odile
Udgivet 2006

Repurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse model

af Müller, Joachim, Aguado-Martínez, Adriana, Manser, Vera, Wong, Ho Ning, Haynes, Richard K., Hemphill, Andrew
Udgivet i Vet Res (2016)

Toward New Transmission-Blocking Combination Therapies: Pharmacokinetics of 10-Amino-Artemisinins and 11-Aza-Artemisinin and Comparison with Dihydroartemisinin and Artemether

af Watson, Daniel J., Laing, Lizahn, Gibhard, Liezl, Wong, Ho Ning, Haynes, Richard K., Wiesner, Lubbe
Udgivet i Antimicrob Agents Chemother (2021)

Artemisone Uptake in Plasmodium falciparum-Infected Erythrocytes

af Pooley, Sophie, Fatih, Farrah A., Krishna, Sanjeev, Gerisch, Michael, Haynes, Richard K., Wong, Ho-Ning, Staines, Henry M.
Udgivet 2011

Evaluation of Artemisone Combinations in Aotus Monkeys Infected with Plasmodium falciparum

af Obaldia, Nicanor, Kotecka, Barbara M., Edstein, Michael D., Haynes, Richard K., Fugmann, Burkhard, Kyle, Dennis E., Rieckmann, Karl H.
Udgivet 2009

Facile Preparation of N-Glycosylated 10-Piperazinyl Artemisinin Derivatives and Evaluation of Their Antimalarial and Cytotoxic Activities

af Wu, Yuet, Parapini, Silvia, Williams, Ian D., Misiano, Paola, Wong, Ho Ning, Taramelli, Donatella, Basilico, Nicoletta, Haynes, Richard K.
Udgivet i Molecules (2018)

Treatment of Murine Cerebral Malaria by Artemisone in Combination with Conventional Antimalarial Drugs: Antiplasmodial Effects and Immune Responses

af Guiguemde, W. Armand, Hunt, Nicholas H., Guo, Jintao, Marciano, Annael, Haynes, Richard K., Clark, Julie, Guy, R. Kiplin, Golenser, Jacob
Udgivet 2014

In Vitro Efficacies, ADME, and Pharmacokinetic Properties of Phenoxazine Derivatives Active against Mycobacterium tuberculosis

af Tanner, Lloyd, Evans, Joanna C., Seldon, Ronnett, Jordaan, Audrey, Warner, Digby F., Haynes, Richard K., Parkinson, Christopher J., Wiesner, Lubbe
Udgivet i Antimicrob Agents Chemother (2019)

Anti-Melanoma Activities of Artemisone and Prenylated Amino-Artemisinins in Combination With Known Anticancer Drugs

af Wong, Ho Ning, Lewies, Angélique, Haigh, Michaela, Viljoen, Joe M., Wentzel, Johannes F., Haynes, Richard K., du Plessis, Lissinda H.
Udgivet i Front Pharmacol (2020)

First Assessment in Humans of the Safety, Tolerability, Pharmacokinetics, and Ex Vivo Pharmacodynamic Antimalarial Activity of the New Artemisinin Derivative Artemisone

af Nagelschmitz, Johannes, Voith, Barbara, Wensing, Georg, Roemer, Axel, Fugmann, Burkhard, Haynes, Richard K., Kotecka, Barbara M., Rieckmann, Karl H., Edstein, Michael D.
Udgivet 2008

Elimination of Schistosoma mansoni in infected mice by slow release of artemisone

af Gold, Daniel, Alian, Mohammed, Domb, Avraham, Karawani, Yara, Jbarien, Maysa, Chollet, Jacques, Haynes, Richard K., Wong, Ho Ning, Buchholz, Viola, Greiner, Andreas, Golenser, Jacob
Udgivet i Int J Parasitol Drugs Drug Resist (2017)