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Artemisinins Inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense In Vitro Growth

Artemisinin compounds inhibit in vitro growth of cultured Trypanosoma cruzi and Trypanosoma brucei rhodesiense at concentrations in the low micromolar range. Artemisinin also inhibits calcium-dependent ATPase activity in T. cruzi membranes, suggesting a mode of action via membrane pumps. Artemisinin...

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Bibliografiske detaljer
Main Authors: Mishina, Yuliya V., Krishna, Sanjeev, Haynes, Richard K., Meade, John C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855540/
https://ncbi.nlm.nih.gov/pubmed/17339374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01544-06
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