Indirubin Analogues Inhibit Trypanosoma brucei Glycogen Synthase Kinase 3 Short and T. brucei Growth

The protozoan parasite Trypanosoma brucei is the causative agent of human African trypanosomiasis (HAT). The disease is fatal if it remains untreated, whereas most drug treatments are inadequate due to high toxicity, difficulties in administration, and low central nervous system penetration. T. bruc...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Efstathiou, Antonia, Gaboriaud-Kolar, Nicolas, Myrianthopoulos, Vassilios, Vougogiannopoulou, Konstantina, Subota, Ines, Aicher, Stephanie, Mikros, Emmanuel, Bastin, Philippe, Skaltsounis, Alexios-Leandros, Soteriadou, Ketty, Smirlis, Despina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2019
Gaiak:
Susceptibility
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535550/
https://ncbi.nlm.nih.gov/pubmed/30910902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02065-18
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