Indirubin Analogues Inhibit Trypanosoma brucei Glycogen Synthase Kinase 3 Short and T. brucei Growth

The protozoan parasite Trypanosoma brucei is the causative agent of human African trypanosomiasis (HAT). The disease is fatal if it remains untreated, whereas most drug treatments are inadequate due to high toxicity, difficulties in administration, and low central nervous system penetration. T. bruc...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Efstathiou, Antonia, Gaboriaud-Kolar, Nicolas, Myrianthopoulos, Vassilios, Vougogiannopoulou, Konstantina, Subota, Ines, Aicher, Stephanie, Mikros, Emmanuel, Bastin, Philippe, Skaltsounis, Alexios-Leandros, Soteriadou, Ketty, Smirlis, Despina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535550/
https://ncbi.nlm.nih.gov/pubmed/30910902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02065-18
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