Indirubin Analogues Inhibit Trypanosoma brucei Glycogen Synthase Kinase 3 Short and T. brucei Growth

The protozoan parasite Trypanosoma brucei is the causative agent of human African trypanosomiasis (HAT). The disease is fatal if it remains untreated, whereas most drug treatments are inadequate due to high toxicity, difficulties in administration, and low central nervous system penetration. T. bruc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Antimicrob Agents Chemother
मुख्य लेखकों: Efstathiou, Antonia, Gaboriaud-Kolar, Nicolas, Myrianthopoulos, Vassilios, Vougogiannopoulou, Konstantina, Subota, Ines, Aicher, Stephanie, Mikros, Emmanuel, Bastin, Philippe, Skaltsounis, Alexios-Leandros, Soteriadou, Ketty, Smirlis, Despina
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2019
विषय:
Susceptibility
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535550/
https://ncbi.nlm.nih.gov/pubmed/30910902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02065-18
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