Development and Validation of a Combined Methodology for Assessing the Total Quality Control of Herbal Medicinal Products – Application to Oleuropein Preparations

Por Lemonakis, Nikolaos, Gikas, Evagelos, Halabalaki, Maria, Skaltsounis, Alexios-Leandros
Publicado em 2013

Oleuropein as an inhibitor of peroxisome proliferator-activated receptor gamma

Por Svobodova, Michaela, Andreadou, Ioanna, Skaltsounis, Alexios-Leandros, Kopecky, Jan, Flachs, Pavel
Publicado em 2013

Modulation of CYP1A1 and CYP1A2 Hepatic Enzymes after Oral Administration of Chios Mastic Gum to Male Wistar Rats

Por Katsanou, Efrosini S., Kyriakopoulou, Katerina, Emmanouil, Christina, Fokialakis, Nikolas, Skaltsounis, Alexios-Leandros, Machera, Kyriaki
Publicado em 2014

The leishmanicidal activity of oleuropein is selectively regulated through inflammation- and oxidative stress-related genes

Por Kyriazis, Ioannis D., Koutsoni, Olga S., Aligiannis, Nektarios, Karampetsou, Kalliopi, Skaltsounis, Alexios-Leandros, Dotsika, Eleni
Publicado no Parasit Vectors (2016)

Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts

Por Sklirou, Aimilia D., Ralli, Marianna, Dominguez, Maria, Papassideri, Issidora, Skaltsounis, Alexios-Leandros, Trougakos, Ioannis P.
Publicado no Redox Biol (2015)

Flavonoid Glycosides Isolated from Unique Legume Plant Extracts as Novel Inhibitors of Xanthine Oxidase

Por Spanou, Chrysoula, Veskoukis, Aristidis S., Kerasioti, Thalia, Kontou, Maria, Angelis, Apostolos, Aligiannis, Nektarios, Skaltsounis, Alexios-Leandros, Kouretas, Dimitrios
Publicado em 2012

High-Level Antimicrobial Efficacy of Representative Mediterranean Natural Plant Extracts against Oral Microorganisms

Por Karygianni, Lamprini, Cecere, Manuel, Skaltsounis, Alexios Leandros, Argyropoulou, Aikaterini, Hellwig, Elmar, Aligiannis, Nektarios, Wittmer, Annette, Al-Ahmad, Ali
Publicado em 2014

In Vitro and In Vivo Activities of Chios Mastic Gum Extracts and Constituents against Helicobacter pylori

Por Paraschos, Sotirios, Magiatis, Prokopios, Mitakou, Sofia, Petraki, Kalliopi, Kalliaropoulos, Antonios, Maragkoudakis, Petros, Mentis, Andreas, Sgouras, Dionyssios, Skaltsounis, Alexios-Leandros
Publicado em 2007

The Bite of the Honeybee: 2-Heptanone Secreted from Honeybee Mandibles during a Bite Acts as a Local Anaesthetic in Insects and Mammals

Por Papachristoforou, Alexandros, Kagiava, Alexia, Papaefthimiou, Chrisovalantis, Termentzi, Aikaterini, Fokialakis, Nikolas, Skaltsounis, Alexios-Leandros, Watkins, Max, Arnold, Gérard, Theophilidis, George
Publicado em 2012

An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial Glycogen Synthase Kinase-3 over leishmanial cdc2-related protein kinase 3

Por Efstathiou, Antonia, Gaboriaud-Kolar, Nicolas, Smirlis, Despina, Myrianthopoulos, Vassilios, Vougogiannopoulou, Konstantina, Alexandratos, Alexandros, Kritsanida, Marina, Mikros, Emmanuel, Soteriadou, Ketty, Skaltsounis, Alexios-Leandros
Publicado em 2014

Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities

Por Guldbrandsen, Niels, De Mieri, Maria, Gupta, Mahabir, Liakou, Eleni, Pratsinis, Harris, Kletsas, Dimitris, Chaita, Eliza, Aligiannis, Nektarios, Skaltsounis, Alexios-Leandros, Hamburger, Matthias
Publicado no Sci Pharm (2015)

Inhibitors of Leishmania mexicana CRK3 Cyclin-Dependent Kinase: Chemical Library Screen and Antileishmanial Activity

Por Grant, Karen M., Dunion, Morag H., Yardley, Vanessa, Skaltsounis, Alexios-Leandros, Marko, Doris, Eisenbrand, Gerhard, Croft, Simon L., Meijer, Laurent, Mottram, Jeremy C.
Publicado em 2004

Soluble 3′, 6-substituted indirubins with enhanced selectivity towards glycogen synthase kinase -3 alter circadian period

Por VOUGOGIANNOPOULOU, Konstantina, FERANDIN, Yoan, BETTAYEB, Karima, MYRIANTHOPOULOS, Vassilios, LOZACH, Olivier, FAN, Yunzhen, JOHNSON, Carl Hirschie, MAGIATIS, Prokopios, SKALTSOUNIS, Alexios-Leandros, MIKROS, Emmanuel, MEIJER, Laurent
Publicado em 2008

Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin

Por Magiatis, Prokopios, Pappas, Periklis, Gaitanis, George, Mexia, Nikitia, Melliou, Eleni, Galanou, Maria, Vlachos, Christophoros, Stathopoulou, Konstantina, Skaltsounis, Alexios Leandros, Marselos, Marios, Velegraki, Aristea, Denison, Michael S., Bassukas, Ioannis D.
Publicado em 2013

Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases

Por Myrianthopoulos, Vassilios, Kritsanida, Marina, Gaboriaud-Kolar, Nicolas, Magiatis, Prokopios, Ferandin, Yoan, Durieu, Emilie, Lozach, Olivier, Cappel, Daniel, Soundararajan, Meera, Filippakopoulos, Panagis, Sherman, Woody, Knapp, Stefan, Meijer, Laurent, Mikros, Emmanuel, Skaltsounis, Alexios-Leandros
Publicado em 2012

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity

Por Durieu, Emilie, Prina, Eric, Leclercq, Olivier, Oumata, Nassima, Gaboriaud-Kolar, Nicolas, Vougogiannopoulou, Konstantina, Aulner, Nathalie, Defontaine, Audrey, No, Joo Hwan, Ruchaud, Sandrine, Skaltsounis, Alexios-Leandros, Galons, Hervé, Späth, Gerald F., Meijer, Laurent, Rachidi, Najma
Publicado no Antimicrob Agents Chemother (2016)

Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Anal...

Por Myrianthopoulos, Vassilios, Gaboriaud-Kolar, Nicolas, Tallant, Cynthia, Hall, Michelle-Lynn, Grigoriou, Stylianos, Brownlee, Peter Moore, Fedorov, Oleg, Rogers, Catherine, Heidenreich, David, Wanior, Marek, Drosos, Nikolaos, Mexia, Nikitia, Savitsky, Pavel, Bagratuni, Tina, Kastritis, Efstathios, Terpos, Evangelos, Filippakopoulos, Panagis, Müller, Susanne, Skaltsounis, Alexios-Leandros, Downs, Jessica Ann, Knapp, Stefan, Mikros, Emmanuel
Publicado no J Med Chem (2016)