Indirubin Analogues Inhibit Trypanosoma brucei Glycogen Synthase Kinase 3 Short and T. brucei Growth

The protozoan parasite Trypanosoma brucei is the causative agent of human African trypanosomiasis (HAT). The disease is fatal if it remains untreated, whereas most drug treatments are inadequate due to high toxicity, difficulties in administration, and low central nervous system penetration. T. bruc...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Efstathiou, Antonia, Gaboriaud-Kolar, Nicolas, Myrianthopoulos, Vassilios, Vougogiannopoulou, Konstantina, Subota, Ines, Aicher, Stephanie, Mikros, Emmanuel, Bastin, Philippe, Skaltsounis, Alexios-Leandros, Soteriadou, Ketty, Smirlis, Despina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535550/
https://ncbi.nlm.nih.gov/pubmed/30910902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02065-18
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