Phenotypic Screens Reveal Posaconazole as a Rapidly Acting Amebicidal Combination Partner for Treatment of Primary Amoebic Meningoencephalitis

af Colon, Beatrice L, Rice, Christopher A, Guy, R Kiplin, Kyle, Dennis E
Udgivet i J Infect Dis (2019)

Discovery of Anti-Amoebic Inhibitors from Screening the MMV Pandemic Response Box on Balamuthia mandrillaris, Naegleria fowleri, and Acanthamoeba castellanii

af Rice, Christopher A., Troth, Emma V., Russell, A. Cassiopeia, Kyle, Dennis E.
Udgivet i Pathogens (2020)

In Vitro Screening of the Open-Source Medicines for Malaria Venture Malaria and Pathogen Boxes To Discover Novel Compounds with Activity against Balamuthia mandrillaris

af Rice, Christopher A., Lares-Jiménez, Luis Fernando, Lares-Villa, Fernando, Kyle, Dennis E.
Udgivet i Antimicrob Agents Chemother (2020)

Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae

af Rice, Christopher A., Colon, Beatrice L., Chen, Emily, Hull, Mitchell V., Kyle, Dennis E.
Udgivet i PLoS Negl Trop Dis (2020)

Bis-Benzimidazole Hits against Naegleria fowleri Discovered with New High-Throughput Screens

af Rice, Christopher A., Colon, Beatrice L., Alp, Mehmet, Göker, Hakan, Boykin, David W., Kyle, Dennis E.
Udgivet i Antimicrob Agents Chemother (2015)

Characterisation of sterol biosynthesis and validation of 14α-demethylase as a drug target in Acanthamoeba

af Thomson, Scott, Rice, Christopher A., Zhang, Tong, Edrada-Ebel, RuAngelie, Henriquez, Fiona L., Roberts, Craig W.
Udgivet i Sci Rep (2017)

Conservation of Ancient Genetic Pathways for Intracellular Persistence Among Animal Pathogenic Bordetellae

af Rivera, Israel, Linz, Bodo, Dewan, Kalyan K., Ma, Longhuan, Rice, Christopher A., Kyle, Dennis E., Harvill, Eric T.
Udgivet i Front Microbiol (2019)

Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials

af Rice, Christopher A., Campbell, Sara J., Bisson, Claudine, Owen, Hayley J., Sedelnikova, Svetlana E., Baker, Patrick J., Rice, David W., Henriquez, Fiona L., Roberts, Craig W.
Udgivet i PLoS One (2018)

Keikipukalides, Furanocembrane Diterpenes from the Antarctic Deep Sea Octocoral Plumarella delicatissima

af Thomas, Santana A. L., von Salm, Jacqueline L., Clark, Shane, Ferlita, Steve, Nemani, Prasanth, Azhari, Ala, Rice, Christopher A., Wilson, Nerida G., Kyle, Dennis E., Baker, Bill J.
Udgivet i J Nat Prod (2017)

Exploitation of Mangrove Endophytic Fungi for Infectious Disease Drug Discovery

af Demers, Danielle H., Knestrick, Matthew A., Fleeman, Renee, Tawfik, Rahmy, Azhari, Ala, Souza, Ashley, Vesely, Brian, Netherton, Mandy, Gupta, Rashmi, Colon, Beatrice L., Rice, Christopher A., Rodríguez-Pérez, Mario A., Rohde, Kyle H., Kyle, Dennis E., Shaw, Lindsey N., Baker, Bill J.
Udgivet i Mar Drugs (2018)

Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba

af Tillery, Logan, Barrett, Kayleigh, Goldstein, Jenna, Lassner, Jared W., Osterhout, Bram, Tran, Nathan L., Xu, Lily, Young, Ryan M., Craig, Justin, Chun, Ian, Dranow, David M., Abendroth, Jan, Delker, Silvia L., Davies, Douglas R., Mayclin, Stephen J., Calhoun, Brandy, Bolejack, Madison J., Staker, Bart, Subramanian, Sandhya, Phan, Isabelle, Lorimer, Donald D., Myler, Peter J., Edwards, Thomas E., Kyle, Dennis E., Rice, Christopher A., Morris, James C., Leahy, James W., Manetsch, Roman, Barrett, Lynn K., Smith, Craig L., Van Voorhis, Wesley C.
Udgivet i PLoS One (2021)

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

af Van Voorhis, Wesley C., Adams, John H., Adelfio, Roberto, Ahyong, Vida, Akabas, Myles H., Alano, Pietro, Alday, Aintzane, Alemán Resto, Yesmalie, Alsibaee, Aishah, Alzualde, Ainhoa, Andrews, Katherine T., Avery, Simon V., Avery, Vicky M., Ayong, Lawrence, Baker, Mark, Baker, Stephen, Ben Mamoun, Choukri, Bhatia, Sangeeta, Bickle, Quentin, Bounaadja, Lotfi, Bowling, Tana, Bosch, Jürgen, Boucher, Lauren E., Boyom, Fabrice F., Brea, Jose, Brennan, Marian, Burton, Audrey, Caffrey, Conor R., Camarda, Grazia, Carrasquilla, Manuela, Carter, Dee, Belen Cassera, Maria, Chih-Chien Cheng, Ken, Chindaudomsate, Worathad, Chubb, Anthony, Colon, Beatrice L., Colón-López, Daisy D., Corbett, Yolanda, Crowther, Gregory J., Cowan, Noemi, D’Alessandro, Sarah, Le Dang, Na, Delves, Michael, DeRisi, Joseph L., Du, Alan Y., Duffy, Sandra, Abd El-Salam El-Sayed, Shimaa, Ferdig, Michael T., Fernández Robledo, José A., Fidock, David A., Florent, Isabelle, Fokou, Patrick V. T., Galstian, Ani, Gamo, Francisco Javier, Gokool, Suzanne, Gold, Ben, Golub, Todd, Goldgof, Gregory M., Guha, Rajarshi, Guiguemde, W. Armand, Gural, Nil, Guy, R. Kiplin, Hansen, Michael A. E., Hanson, Kirsten K., Hemphill, Andrew, Hooft van Huijsduijnen, Rob, Horii, Takaaki, Horrocks, Paul, Hughes, Tyler B., Huston, Christopher, Igarashi, Ikuo, Ingram-Sieber, Katrin, Itoe, Maurice A., Jadhav, Ajit, Naranuntarat Jensen, Amornrat, Jensen, Laran T., Jiang, Rays H. Y., Kaiser, Annette, Keiser, Jennifer, Ketas, Thomas, Kicka, Sebastien, Kim, Sunyoung, Kirk, Kiaran, Kumar, Vidya P., Kyle, Dennis E., Lafuente, Maria Jose, Landfear, Scott, Lee, Nathan, Lee, Sukjun, Lehane, Adele M., Li, Fengwu, Little, David, Liu, Liqiong, Llinás, Manuel, Loza, Maria I., Lubar, Aristea, Lucantoni, Leonardo, Lucet, Isabelle, Maes, Louis, Mancama, Dalu, Mansour, Nuha R., March, Sandra, McGowan, Sheena, Medina Vera, Iset, Meister, Stephan, Mercer, Luke, Mestres, Jordi, Mfopa, Alvine N., Misra, Raj N., Moon, Seunghyun, Moore, John P., Morais Rodrigues da Costa, Francielly, Müller, Joachim, Muriana, Arantza, Nakazawa Hewitt, Stephen, Nare, Bakela, Nathan, Carl, Narraidoo, Nathalie, Nawaratna, Sujeevi, Ojo, Kayode K., Ortiz, Diana, Panic, Gordana, Papadatos, George, Parapini, Silvia, Patra, Kailash, Pham, Ngoc, Prats, Sarah, Plouffe, David M., Poulsen, Sally-Ann, Pradhan, Anupam, Quevedo, Celia, Quinn, Ronald J., Rice, Christopher A., Abdo Rizk, Mohamed, Ruecker, Andrea, St. Onge, Robert, Salgado Ferreira, Rafaela, Samra, Jasmeet, Robinett, Natalie G., Schlecht, Ulrich, Schmitt, Marjorie, Silva Villela, Filipe, Silvestrini, Francesco, Sinden, Robert, Smith, Dennis A., Soldati, Thierry, Spitzmüller, Andreas, Stamm, Serge Maximilian, Sullivan, David J., Sullivan, William, Suresh, Sundari, Suzuki, Brian M., Suzuki, Yo, Swamidass, S. Joshua, Taramelli, Donatella, Tchokouaha, Lauve R. Y., Theron, Anjo, Thomas, David, Tonissen, Kathryn F., Townson, Simon, Tripathi, Abhai K., Trofimov, Valentin, Udenze, Kenneth O., Ullah, Imran, Vallieres, Cindy, Vigil, Edgar, Vinetz, Joseph M., Voong Vinh, Phat, Vu, Hoan, Watanabe, Nao-aki, Weatherby, Kate, White, Pamela M., Wilks, Andrew F., Winzeler, Elizabeth A., Wojcik, Edward, Wree, Melanie, Wu, Wesley, Yokoyama, Naoaki, Zollo, Paul H. A., Abla, Nada, Blasco, Benjamin, Burrows, Jeremy, Laleu, Benoît, Leroy, Didier, Spangenberg, Thomas, Wells, Timothy, Willis, Paul A.
Udgivet i PLoS Pathog (2016)