Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials

Acanthamoeba is normally free-living, but sometimes facultative and occasionally opportunistic parasites. Current therapies are, by necessity, arduous and yet poorly effective due to their inabilities to kill cyst stages or in some cases to actually induce encystation. Acanthamoeba can therefore sur...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rice, Christopher A., Campbell, Sara J., Bisson, Claudine, Owen, Hayley J., Sedelnikova, Svetlana E., Baker, Patrick J., Rice, David W., Henriquez, Fiona L., Roberts, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029752/
https://ncbi.nlm.nih.gov/pubmed/29969448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198827
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