Enzymic degradation of plasma arginine using arginine deiminase inhibits nitric oxide production and protects mice from the lethal effects of tumour necrosis factor alpha and endot...

Por Thomas, J Brandon, Holtsberg, Frederick W, Ensor, C Mark, Bomalaski, John S, Clark, Mike A
Publicado em 2002

Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs

Por Adhikari, Rajan P., Kort, Thomas, Shulenin, Sergey, Kanipakala, Tulasikumari, Ganjbaksh, Nader, Roghmann, Mary-Claire, Holtsberg, Frederick W., Aman, M. Javad
Publicado no PLoS One (2015)

Correction: Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs

Por Adhikari, Rajan P., Kort, Thomas, Shulenin, Sergey, Kanipakala, Tulasikumari, Ganjbaksh, Nader, Roghmann, Mary-Claire, Holtsberg, Frederick W., Aman, M. Javad
Publicado no PLoS One (2015)

Quantitative Serology Assays for Determination of Antibody Responses to Ebola Virus Glycoprotein and Matrix Protein in Nonhuman Primates and Humans

Por Vu, Hong, Shulenin, Sergey, Grolla, Allen, Audet, Jonathan, He, Shihua, Kobinger, Gary, Unfer, Robert C., Warfield, Kelly L., Aman, M. Javad, Holtsberg, Frederick W.
Publicado no Antiviral Res (2015)

Homologous and Heterologous Protection of Nonhuman Primates by Ebola and Sudan Virus-Like Particles

Por Warfield, Kelly L., Dye, John M., Wells, Jay B., Unfer, Robert C., Holtsberg, Frederick W., Shulenin, Sergey, Vu, Hong, Swenson, Dana L., Bavari, Sina, Aman, M. Javad
Publicado no PLoS One (2015)

A Tripartite Cocktail of Chimeric Monoclonal Antibodies Passively Protects Mice against Ricin, Staphylococcal Enterotoxin B and Clostridium perfringens Epsilon Toxin

Por Sully, Erin K., Whaley, Kevin, Bohorova, Natasha, Bohorov, Ognian, Goodman, Charles, Kim, Do, Pauly, Michael, Velasco, Jesus, Holtsberg, Frederick W., Stavale, Eric, Aman, M. Javad, Tangudu, Chandra, Uzal, Francisco A., Mantis, Nicholas J., Zeitlin, Larry
Publicado no Toxicon (2014)

Safety and Immunogenicity of a Parenterally Administered, Structure-Based Rationally Modified Recombinant Staphylococcal Enterotoxin B Protein Vaccine, STEBVax

Por Chen, Wilbur H., Pasetti, Marcela F., Adhikari, Rajan P., Baughman, Holly, Douglas, Robin, El-Khorazaty, Jill, Greenberg, Nancy, Holtsberg, Frederick W., Liao, Grant C., Reymann, Mardi K., Wang, Xiaolin, Warfield, Kelly L., Aman, M. Javad
Publicado no Clin Vaccine Immunol (2016)

Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute HCV infection

Por Keck, Zhen-Yong, Wang, Yong, Lau, Patrick, Lund, Garry, Rangarajan, Sneha, Fauvelle, Catherine, Liao, Grant C., Holtsberg, Frederick W., Warfield, Kelly L., Aman, M. Javad, Pierce, Brian G., Fuerst, Thomas R., Bailey, Justin R., Baumert, Thomas F., Mariuzza, Roy A., Kneteman, Norman M., Foung, Steven K. H.
Publicado no Hepatology (2016)

Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs

Por Fusco, Marnie L., Hashiguchi, Takao, Cassan, Robyn, Biggins, Julia E., Murin, Charles D., Warfield, Kelly L., Li, Sheng, Holtsberg, Frederick W., Shulenin, Sergey, Vu, Hong, Olinger, Gene G., Kim, Do H., Whaley, Kevin J., Zeitlin, Larry, Ward, Andrew B., Nykiforuk, Cory, Aman, M. Javad, Berry, Jody, Saphire, Erica Ollmann
Publicado no PLoS Pathog (2015)

Correction: Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs

Por Fusco, Marnie L., Hashiguchi, Takao, Cassan, Robyn, Biggins, Julia E., Murin, Charles D., Warfield, Kelly L., Li, Sheng, Holtsberg, Frederick W., Shulenin, Sergey, Vu, Hong, Olinger, Gene G., Kim, Do H., Whaley, Kevin J., Zeitlin, Larry, Ward, Andrew B., Nykiforuk, Cory, Aman, M. Javad, Berry, Jody D., Saphire, Erica Ollmann
Publicado no PLoS Pathog (2015)

Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein

Por Keck, Zhen-Yong, Enterlein, Sven G., Howell, Katie A., Vu, Hong, Shulenin, Sergey, Warfield, Kelly L., Froude, Jeffrey W., Araghi, Nazli, Douglas, Robin, Biggins, Julia, Lear-Rooney, Calli M., Wirchnianski, Ariel S., Lau, Patrick, Wang, Yong, Herbert, Andrew S., Dye, John M., Glass, Pamela J., Holtsberg, Frederick W., Foung, Steven K. H., Aman, M. Javad
Publicado no J Virol (2015)

A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses

Por Wec, Anna Z., Nyakatura, Elisabeth K., Herbert, Andrew S., Howell, Katie A., Holtsberg, Frederick W., Bakken, Russell R., Mittler, Eva, Christin, John R., Shulenin, Sergey, Jangra, Rohit K., Bharrhan, Sushma, Kuehne, Ana I., Bornholdt, Zachary A., Flyak, Andrew I., Saphire, Erica Ollmann, Crowe, James E, Aman, M. Javad, Dye, John M., Lai, Jonathan R., Chandran, Kartik
Publicado no Science (2016)

Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses

Por Holtsberg, Frederick W., Shulenin, Sergey, Vu, Hong, Howell, Katie A., Patel, Sonal J., Gunn, Bronwyn, Karim, Marcus, Lai, Jonathan R., Frei, Julia C., Nyakatura, Elisabeth K., Zeitlin, Larry, Douglas, Robin, Fusco, Marnie L., Froude, Jeffrey W., Saphire, Erica Ollmann, Herbert, Andrew S., Wirchnianski, Ariel S., Lear-Rooney, Calli M., Alter, Galit, Dye, John M., Glass, Pamela J., Warfield, Kelly L., Aman, M. Javad
Publicado no J Virol (2015)

Immunization-elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability

Por Zhao, Xuelian, Howell, Katie A., He, Shihua, Brannan, Jennifer M., Wec, Anna Z., Davidson, Edgar, Turner, Hannah L., Chiang, Chi-I, Lei, Lin, Fels, J. Maximilian, Vu, Hong, Shulenin, Sergey, Turonis, Ashley N., Kuehne, Ana I., Liu, Guodong, Ta, Mi, Wang, Yimeng, Sundling, Christopher, Xiao, Yongli, Spence, Jennifer S., Doranz, Benjamin J., Holtsberg, Frederick W., Ward, Andrew B., Chandran, Kartik, Dye, John M., Qiu, Xiangguo, Li, Yuxing, Aman, M. Javad
Publicado no Cell (2017)

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

Por Howell, Katie A., Qiu, Xiangguo, Brannan, Jennifer M., Bryan, Christopher, Davidson, Edgar, Holtsberg, Frederick W., Wec, Anna Z., Shulenin, Sergey, Biggins, Julia E., Douglas, Robin, Enterlein, Sven G., Turner, Hannah L., Pallesen, Jesper, Murin, Charles D., He, Shihua, Kroeker, Andrea, Vu, Hong, Herbert, Andrew S., Fusco, Marnie L., Nyakatura, Elisabeth K., Lai, Jonathan R., Keck, Zhen-Yong, Foung, Steven K.H., Saphire, Erica Ollmann, Zeitlin, Larry, Ward, Andrew B., Chandran, Kartik, Doranz, Benjamin J., Kobinger, Gary P., Dye, John M., Aman, M. Javad
Publicado no Cell Rep (2016)