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A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses
There is an urgent need for monoclonal antibody (mAb) therapies that broadly protect against Ebola virus and other filoviruses. The conserved, essential interaction between the filovirus glycoprotein, GP, and its entry receptor Niemann-Pick C1 (NPC1) provides an attractive target for such mAbs but i...
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| Publicado en: | Science |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5647781/ https://ncbi.nlm.nih.gov/pubmed/27608667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aag3267 |
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