A Shared Structural Solution for Neutralizing Ebolaviruses

Sudan virus (genus ebolavirus) is lethal, yet no monoclonal antibody is known to neutralize it. Here we describe antibody 16F6 that neutralizes Sudan virus and present its structure bound to the trimeric viral glycoprotein. Unexpectedly, the 16F6 epitope overlaps that of KZ52, the only other antibod...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dias, João M., Kuehne, Ana I., Abelson, Dafna M., Bale, Shridhar, Wong, Anthony C., Halfmann, Peter, Muhammad, Majidat A., Fusco, Marnie L., Zak, Samantha E., Kang, Eugene, Kawaoka, Yoshihiro, Chandran, Kartik, Dye, John M., Saphire, Erica Ollmann
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230659/
https://ncbi.nlm.nih.gov/pubmed/22101933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2150
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados