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Neutralizing Ebolavirus: structural insights into the envelope glycoprotein and antibodies targeted against it

The ebolavirus (EBOV) envelope glycoprotein (GP) is solely responsible for viral attachment to, fusion with, and entry of new host cells, and consequently is a major target of vaccine design efforts. Recently determined crystal structures of key antibodies in complex with their EBOV epitopes have pr...

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Détails bibliographiques
Auteurs principaux: Lee, Jeffrey E., Saphire, Erica Ollmann
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759674/
https://ncbi.nlm.nih.gov/pubmed/19559599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.05.004
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