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Neutralizing Ebolavirus: structural insights into the envelope glycoprotein and antibodies targeted against it

The ebolavirus (EBOV) envelope glycoprotein (GP) is solely responsible for viral attachment to, fusion with, and entry of new host cells, and consequently is a major target of vaccine design efforts. Recently determined crystal structures of key antibodies in complex with their EBOV epitopes have pr...

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Detalhes bibliográficos
Main Authors: Lee, Jeffrey E., Saphire, Erica Ollmann
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759674/
https://ncbi.nlm.nih.gov/pubmed/19559599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.05.004
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