Chimeric Filoviruses for Identification and Characterization of Monoclonal Antibodies

Por Ilinykh, Philipp A., Shen, Xiaoli, Flyak, Andrew I., Kuzmina, Natalia, Ksiazek, Thomas G., Crowe, James E., Bukreyev, Alexander
Publicado no J Virol (2016)

Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

Por Bornholdt, Zachary A., Ndungo, Esther, Fusco, Marnie L., Bale, Shridhar, Flyak, Andrew I., Crowe, James E., Chandran, Kartik, Saphire, Erica Ollmann
Publicado no mBio (2016)

Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms

Por Mankowski, Madeleine C., Kinchen, Valerie J., Wasilewski, Lisa N., Flyak, Andrew I., Ray, Stuart C., Crowe, James E., Bailey, Justin R.
Publicado no Proc Natl Acad Sci U S A (2018)

Structural basis for Marburg virus neutralization by a cross-reactive human antibody

Por Hashiguchi, Takao, Fusco, Marnie L., Bornholdt, Zachary A., Lee, Jeffrey E., Flyak, Andrew I., Matsuoka, Rei, Kohda, Daisuke, Yanagi, Yusuke, Hammel, Michal, Crowe, James E., Saphire, Erica Ollmann
Publicado no Cell (2015)

IL-15 regulates homeostasis and terminal maturation of NKT cells()

Por Gordy, Laura E., Bezbradica, Jelena S., Flyak, Andrew I., Spencer, Charles T., Dunkle, Alexis, Sun, Jingchun, Stanic, Aleksandar K., Boothby, Mark R., He, You-Wen, Zhao, Zhongming, Van Kaer, Luc, Joyce, Sebastian
Publicado em 2011

Structures of Ebola Virus GP and sGP in Complex with Therapeutic Antibodies

Por Pallesen, Jesper, Murin, Charles D., de Val, Natalia, Cottrell, Christopher A., Hastie, Kathryn M., Turner, Hannah L., Fusco, Marnie L., Flyak, Andrew I., Zeitlin, Larry, Crowe, James E., Andersen, Kristian G., Saphire, Erica Ollmann, Ward, Andrew B.
Publicado no Nat Microbiol (2016)

The Marburgvirus-neutralizing human monoclonal antibody MR191 targets a conserved site to block virus receptor binding

Por King, Liam B., Fusco, Marnie L., Flyak, Andrew I., Ilinykh, Philipp A., Huang, Kai, Gunn, Bronwyn, Kirchdoerfer, Robert N., Hastie, Kathryn M., Sangha, Amandeep K., Meiler, Jens, Alter, Galit, Bukreyev, Alexander, Crowe, James E., Saphire, Erica Ollmann
Publicado no Cell Host Microbe (2018)

Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus

Por Flyak, Andrew I., Ilinykh, Philipp A., Murin, Charles D., Garron, Tania, Shen, Xiaoli, Fusco, Marnie L., Hashiguchi, Takao, Bornholdt, Zachary A., Slaughter, James C., Sapparapu, Gopal, Klages, Curtis, Ksiazek, Thomas G., Ward, Andrew B., Saphire, Erica Ollmann, Bukreyev, Alexander, Crowe, James E.
Publicado no Cell (2015)

Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance

Por Bailey, Justin R., Flyak, Andrew I., Cohen, Valerie J., Li, Hui, Wasilewski, Lisa N., Snider, Anna E., Wang, Shuyi, Learn, Gerald H., Kose, Nurgun, Loerinc, Leah, Lampley, Rebecca, Cox, Andrea L., Pfaff, Jennifer M., Doranz, Benjamin J., Shaw, George M., Ray, Stuart C., Crowe, James E.
Publicado no JCI Insight (2017)

Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody

Por Mire, Chad E., Geisbert, Joan B., Borisevich, Viktoriya, Fenton, Karla A., Agans, Krystle N., Flyak, Andrew I., Deer, Daniel J., Steinkellner, Herta, Bohorov, Ognian, Bohorova, Natasha, Goodman, Charles, Hiatt, Andrew, Kim, Do H., Pauly, Michael H., Velasco, Jesus, Whaley, Kevin J., Crowe, James E., Zeitlin, Larry, Geisbert, Thomas W.
Publicado no Sci Transl Med (2017)

A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses

Por Wec, Anna Z., Nyakatura, Elisabeth K., Herbert, Andrew S., Howell, Katie A., Holtsberg, Frederick W., Bakken, Russell R., Mittler, Eva, Christin, John R., Shulenin, Sergey, Jangra, Rohit K., Bharrhan, Sushma, Kuehne, Ana I., Bornholdt, Zachary A., Flyak, Andrew I., Saphire, Erica Ollmann, Crowe, James E, Aman, M. Javad, Dye, John M., Lai, Jonathan R., Chandran, Kartik
Publicado no Science (2016)

CROSS-REACTIVE AND POTENT NEUTRALIZING ANTIBODY RESPONSES IN HUMAN SURVIVORS OF NATURAL EBOLAVIRUS INFECTION

Por Flyak, Andrew I., Shen, Xiaoli, Murin, Charles D., Turner, Hannah L., David, Joshua A., Fusco, Marnie L., Lampley, Rebecca, Kose, Nurgun, Ilinykh, Philipp A., Kuzmina, Natalia, Branchizio, Andre, King, Hannah, Brown, Leland, Bryan, Christopher, Davidson, Edgar, Doranz, Benjamin J., Slaughter, James C., Sapparapu, Gopal, Klages, Curtis, Ksiazek, Thomas G., Saphire, Erica Ollmann, Ward, Andrew B., Bukreyev, Alexander, Crowe, James E.
Publicado no Cell (2016)