Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus

The mechanisms by which neutralizing antibodies inhibit Marburg virus (MARV) are not known. We isolated a panel of neutralizing antibodies from a human MARV survivor that bind to MARV glycoprotein (GP) and compete for binding to a single major antigenic site. Remarkably, several of the antibodies al...

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Udgivet i:Cell
Main Authors: Flyak, Andrew I., Ilinykh, Philipp A., Murin, Charles D., Garron, Tania, Shen, Xiaoli, Fusco, Marnie L., Hashiguchi, Takao, Bornholdt, Zachary A., Slaughter, James C., Sapparapu, Gopal, Klages, Curtis, Ksiazek, Thomas G., Ward, Andrew B., Saphire, Erica Ollmann, Bukreyev, Alexander, Crowe, James E.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344968/
https://ncbi.nlm.nih.gov/pubmed/25723164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.01.031
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