Structural basis for Marburg virus neutralization by a cross-reactive human antibody

The filoviruses, including Marburg and Ebola, express a single glycoprotein on their surface, termed GP, which is responsible for attachment and entry of target cells. Filovirus GPs differ by up to 70% in protein sequence, and no antibodies are yet described that cross-react among them. Here, we pre...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Hashiguchi, Takao, Fusco, Marnie L., Bornholdt, Zachary A., Lee, Jeffrey E., Flyak, Andrew I., Matsuoka, Rei, Kohda, Daisuke, Yanagi, Yusuke, Hammel, Michal, Crowe, James E., Saphire, Erica Ollmann
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344967/
https://ncbi.nlm.nih.gov/pubmed/25723165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.01.041
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