A carregar...

Role of non-local interactions between complementarity determining region loops in binding affinity of MR78 antibody to Marburg virus glycoprotein

An atomic-detail model of the Marburg virus glycoprotein in complex with a neutralizing human monoclonal antibody designated MR78 was constructed using Phenix.Rosetta starting from a 3.6Å crystallographic density map. The Asp at T6 in the HCDR3’s bulged torso cannot form the canonical salt bridge as...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Structure
Main Authors: Sangha, Amandeep K., Dong, Jinhui, Williamson, Lauren, Hashiguchi, Takao, Saphire, Erica Ollmann, Crowe, James E., Meiler, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718948/
https://ncbi.nlm.nih.gov/pubmed/29153506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.10.005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!