BROADLY NEUTRALIZING ANTIBODIES FROM HUMAN SURVIVORS TARGET A CONSERVED SITE IN THE EBOLA VIRUS GLYCOPROTEIN HR2/MPER REGION

Ebola virus (EBOV) in humans causes a severe illness with high mortality rates. Several strategies have been developed in the past to treat EBOV infection, including the antibody cocktail ZMapp(TM) that has been shown to be effective in nonhuman primate models of infection(1) and has been used under...

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Publicado no:Nat Microbiol
Main Authors: Flyak, Andrew I., Kuzmina, Natalia, Murin, Charles D., Bryan, Christopher, Davidson, Edgar, Gilchuk, Pavlo, Gulka, Christopher P., Ilinykh, Philipp A., Shen, Xiaoli, Huang, Kai, Ramanathan, Palaniappan, Turner, Hannah, Fusco, Marnie L., Lampley, Rebecca, Kose, Nurgun, King, Hannah, Sapparapu, Gopal, Doranz, Benjamin J., Ksiazek, Thomas G., Wright, David W., Saphire, Erica Ollmann, Ward, Andrew B., Bukreyev, Alexander, Crowe, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030461/
https://ncbi.nlm.nih.gov/pubmed/29736037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0157-z
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