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Structures of Ebola Virus GP and sGP in Complex with Therapeutic Antibodies

The Ebola virus (EBOV) GP gene encodes two glycoproteins. The major product is a soluble, dimeric glycoprotein termed sGP that is secreted abundantly. Despite the abundance of sGP during infection, little is known regarding its structure or functional role. A minor product, resulting from transcript...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Pallesen, Jesper, Murin, Charles D., de Val, Natalia, Cottrell, Christopher A., Hastie, Kathryn M., Turner, Hannah L., Fusco, Marnie L., Flyak, Andrew I., Zeitlin, Larry, Crowe, James E., Andersen, Kristian G., Saphire, Erica Ollmann, Ward, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003320/
https://ncbi.nlm.nih.gov/pubmed/27562261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.128
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