Structures of protective antibodies reveal sites of vulnerability on Ebola virus

Ebola virus (EBOV) and related filoviruses cause severe hemorrhagic fever, with up to 90% lethality, and no treatments are approved for human use. Multiple recent outbreaks of EBOV and the likelihood of future human exposure highlight the need for pre- and postexposure treatments. Monoclonal antibod...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Murin, Charles D., Fusco, Marnie L., Bornholdt, Zachary A., Qiu, Xiangguo, Olinger, Gene G., Zeitlin, Larry, Kobinger, Gary P., Ward, Andrew B., Saphire, Erica Ollmann
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260551/
https://ncbi.nlm.nih.gov/pubmed/25404321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414164111
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