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Structure of the Ebola virus glycoprotein bound to a human survivor antibody
Ebola virus (EBOV) entry requires the surface glycoprotein, GP, to initiate attachment and fusion of viral and host membranes. Here, we report the crystal structure of EBOV GP in its trimeric, pre-fusion conformation (GP1+GP2) bound to a neutralizing antibody, KZ52, derived from a human survivor of...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700032/ https://ncbi.nlm.nih.gov/pubmed/18615077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07082 |
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