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Structure of the Ebola virus glycoprotein bound to a human survivor antibody
Ebola virus (EBOV) entry requires the surface glycoprotein, GP, to initiate attachment and fusion of viral and host membranes. Here, we report the crystal structure of EBOV GP in its trimeric, pre-fusion conformation (GP1+GP2) bound to a neutralizing antibody, KZ52, derived from a human survivor of...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700032/ https://ncbi.nlm.nih.gov/pubmed/18615077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07082 |
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