Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs

S. aureus vaccine development has proven particularly difficult. The conventional approach to achieve sterile immunity through opsonophagocytic killing has been largely unsuccessful. S. aureus is highly toxigenic and a great body of evidence suggests that a successful future vaccine for this organis...

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Udgivet i:PLoS One
Main Authors: Adhikari, Rajan P., Kort, Thomas, Shulenin, Sergey, Kanipakala, Tulasikumari, Ganjbaksh, Nader, Roghmann, Mary-Claire, Holtsberg, Frederick W., Aman, M. Javad
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569305/
https://ncbi.nlm.nih.gov/pubmed/26367030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137874
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