Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs

S. aureus vaccine development has proven particularly difficult. The conventional approach to achieve sterile immunity through opsonophagocytic killing has been largely unsuccessful. S. aureus is highly toxigenic and a great body of evidence suggests that a successful future vaccine for this organis...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Adhikari, Rajan P., Kort, Thomas, Shulenin, Sergey, Kanipakala, Tulasikumari, Ganjbaksh, Nader, Roghmann, Mary-Claire, Holtsberg, Frederick W., Aman, M. Javad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569305/
https://ncbi.nlm.nih.gov/pubmed/26367030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137874
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