Structurally Designed Attenuated Subunit Vaccines for S. aureus LukS-PV and LukF-PV Confer Protection in a Mouse Bacteremia Model

Previous efforts towards S. aureus vaccine development have largely focused on cell surface antigens to induce opsonophagocytic killing aimed at providing sterile immunity, a concept successfully applied to other Gram-positive pathogens such as Streptococcus pneumoniae. However, these approaches hav...

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Detalhes bibliográficos
Main Authors: Karauzum, Hatice, Adhikari, Rajan P., Sarwar, Jawad, Devi, V. Sathya, Abaandou, Laura, Haudenschild, Christian, Mahmoudieh, Mahta, Boroun, Atefeh R., Vu, Hong, Nguyen, Tam, Warfield, Kelly L., Shulenin, Sergey, Aman, M. Javad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676412/
https://ncbi.nlm.nih.gov/pubmed/23762356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065384
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