Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs

The filoviruses, which include the marburg- and ebolaviruses, have caused multiple outbreaks among humans this decade. Antibodies against the filovirus surface glycoprotein (GP) have been shown to provide life-saving therapy in nonhuman primates, but such antibodies are generally virus-specific. Man...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Fusco, Marnie L., Hashiguchi, Takao, Cassan, Robyn, Biggins, Julia E., Murin, Charles D., Warfield, Kelly L., Li, Sheng, Holtsberg, Frederick W., Shulenin, Sergey, Vu, Hong, Olinger, Gene G., Kim, Do H., Whaley, Kevin J., Zeitlin, Larry, Ward, Andrew B., Nykiforuk, Cory, Aman, M. Javad, Berry, Jody, Saphire, Erica Ollmann
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482612/
https://ncbi.nlm.nih.gov/pubmed/26115029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005016
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