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Pharmacokinetic mAb–mAb Interaction: Anti-VEGF mAb Decreases the Distribution of Anti-CEA mAb into Colorectal Tumor Xenografts

To date, there has been little investigation of the risk for drug–drug interactions involving monoclonal antibodies. The present work examined the effects of an anti-vascular endothelial growth factor (anti-VEGF) antibody on the plasma, tissue, and tumor disposition of T84.66, an anti-carcinoembryon...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Abuqayyas, Lubna, Balthasar, Joseph P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385816/
https://ncbi.nlm.nih.gov/pubmed/22528507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9357-2
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