Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute HCV infection

Direct acting antivirals (DAAs) have led to a high cure rate in treated patients with chronic hepatitis C virus (HCV) infection but this still leaves a large number of treatment failures secondary to the emergence of resistance-associated variants (RAVs). To increase the barrier to resistance, a com...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hepatology
Egile Nagusiak: Keck, Zhen-Yong, Wang, Yong, Lau, Patrick, Lund, Garry, Rangarajan, Sneha, Fauvelle, Catherine, Liao, Grant C., Holtsberg, Frederick W., Warfield, Kelly L., Aman, M. Javad, Pierce, Brian G., Fuerst, Thomas R., Bailey, Justin R., Baumert, Thomas F., Mariuzza, Roy A., Kneteman, Norman M., Foung, Steven K. H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115987/
https://ncbi.nlm.nih.gov/pubmed/27641232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28850
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