Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute HCV infection

Direct acting antivirals (DAAs) have led to a high cure rate in treated patients with chronic hepatitis C virus (HCV) infection but this still leaves a large number of treatment failures secondary to the emergence of resistance-associated variants (RAVs). To increase the barrier to resistance, a com...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Hepatology
Asıl Yazarlar: Keck, Zhen-Yong, Wang, Yong, Lau, Patrick, Lund, Garry, Rangarajan, Sneha, Fauvelle, Catherine, Liao, Grant C., Holtsberg, Frederick W., Warfield, Kelly L., Aman, M. Javad, Pierce, Brian G., Fuerst, Thomas R., Bailey, Justin R., Baumert, Thomas F., Mariuzza, Roy A., Kneteman, Norman M., Foung, Steven K. H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115987/
https://ncbi.nlm.nih.gov/pubmed/27641232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28850
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