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Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute HCV infection
Direct acting antivirals (DAAs) have led to a high cure rate in treated patients with chronic hepatitis C virus (HCV) infection but this still leaves a large number of treatment failures secondary to the emergence of resistance-associated variants (RAVs). To increase the barrier to resistance, a com...
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| Publicado no: | Hepatology |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115987/ https://ncbi.nlm.nih.gov/pubmed/27641232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28850 |
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