Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses

The unprecedented 2014-2015 Ebola virus disease (EVD) outbreak in West Africa has highlighted the need for effective therapeutics against filoviruses. Monoclonal antibody (MAb) cocktails have shown great potential as EVD therapeutics; however, the existing protective MAbs are virus species specific....

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Publicado en:J Virol
Autores principales: Holtsberg, Frederick W., Shulenin, Sergey, Vu, Hong, Howell, Katie A., Patel, Sonal J., Gunn, Bronwyn, Karim, Marcus, Lai, Jonathan R., Frei, Julia C., Nyakatura, Elisabeth K., Zeitlin, Larry, Douglas, Robin, Fusco, Marnie L., Froude, Jeffrey W., Saphire, Erica Ollmann, Herbert, Andrew S., Wirchnianski, Ariel S., Lear-Rooney, Calli M., Alter, Galit, Dye, John M., Glass, Pamela J., Warfield, Kelly L., Aman, M. Javad
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702560/
https://ncbi.nlm.nih.gov/pubmed/26468533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02171-15
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