Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses

The unprecedented 2014-2015 Ebola virus disease (EVD) outbreak in West Africa has highlighted the need for effective therapeutics against filoviruses. Monoclonal antibody (MAb) cocktails have shown great potential as EVD therapeutics; however, the existing protective MAbs are virus species specific....

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Veröffentlicht in:J Virol
Hauptverfasser: Holtsberg, Frederick W., Shulenin, Sergey, Vu, Hong, Howell, Katie A., Patel, Sonal J., Gunn, Bronwyn, Karim, Marcus, Lai, Jonathan R., Frei, Julia C., Nyakatura, Elisabeth K., Zeitlin, Larry, Douglas, Robin, Fusco, Marnie L., Froude, Jeffrey W., Saphire, Erica Ollmann, Herbert, Andrew S., Wirchnianski, Ariel S., Lear-Rooney, Calli M., Alter, Galit, Dye, John M., Glass, Pamela J., Warfield, Kelly L., Aman, M. Javad
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702560/
https://ncbi.nlm.nih.gov/pubmed/26468533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02171-15
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