Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein

Ebolaviruses cause severe disease in humans, and identification of monoclonal antibodies (mAbs) that are effective against multiple ebolaviruses are important for therapeutics development. Here we describe a distinct class of broadly neutralizing human mAbs with protective capacity against three ebo...

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Опубликовано в: :Immunity
Главные авторы: Gilchuk, Pavlo, Kuzmina, Natalia, Ilinykh, Philipp A., Huang, Kai, Gunn, Bronwyn M., Bryan, Aubrey, Davidson, Edgar, Doranz, Benjamin J., Turner, Hannah L., Fusco, Marnie L., Bramble, Matthew S., Hoff, Nicole A., Binshtein, Elad, Kose, Nurgun, Flyak, Andrew I., Flinko, Robin, Orlandi, Chiara, Carnahan, Robert, Parrish, Erica H., Sevy, Alexander M., Bombardi, Robin G., Singh, Prashant K., Mukadi, Patrick, Muyembe-Tamfum, Jean Jacques, Ohi, Melanie D., Saphire, Erica Ollmann, Lewis, George K., Alter, Galit, Ward, Andrew B., Rimoin, Anne W., Bukreyev, Alexander, Crowe, James E.
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104738/
https://ncbi.nlm.nih.gov/pubmed/30029854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.06.018
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