Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma

Three clinically relevant ebolaviruses – Ebola (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) viruses, are responsible for severe disease and occasional deadly outbreaks in Africa. The largest Ebola virus disease (EVD) epidemic to date in 2013-2016 in West Africa highlighted the urgent need for counter...

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Spremljeno u:
Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Gilchuk, Pavlo, Guthals, Adrian, Bonissone, Stefano R., Shaw, Jared B., Ilinykh, Philipp A., Huang, Kai, Bombardi, Robin G., Liang, Jenny, Grinyo, Ariadna, Davidson, Edgar, Chen, Elaine C., Gunn, Bronwyn M., Alter, Galit, Saphire, Erica Ollmann, Doranz, Benjamin J., Bukreyev, Alexander, Zeitlin, Larry, Castellana, Natalie, Crowe, James E.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Immunology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322977/
https://ncbi.nlm.nih.gov/pubmed/34335620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.706757
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