Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma

Three clinically relevant ebolaviruses – Ebola (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) viruses, are responsible for severe disease and occasional deadly outbreaks in Africa. The largest Ebola virus disease (EVD) epidemic to date in 2013-2016 in West Africa highlighted the urgent need for counter...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Gilchuk, Pavlo, Guthals, Adrian, Bonissone, Stefano R., Shaw, Jared B., Ilinykh, Philipp A., Huang, Kai, Bombardi, Robin G., Liang, Jenny, Grinyo, Ariadna, Davidson, Edgar, Chen, Elaine C., Gunn, Bronwyn M., Alter, Galit, Saphire, Erica Ollmann, Doranz, Benjamin J., Bukreyev, Alexander, Zeitlin, Larry, Castellana, Natalie, Crowe, James E.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322977/
https://ncbi.nlm.nih.gov/pubmed/34335620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.706757
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