Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap

Recent studies suggest that some monoclonal antibodies (mAbs) specific for ebolavirus glycoprotein (GP) can protect experimental animals against infections. Most mAbs isolated from ebolavirus survivors appeared to target the glycan cap or the stalk region of the viral GP, which is the envelope prote...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Ilinykh, Philipp A., Santos, Rodrigo I., Gunn, Bronwyn M., Kuzmina, Natalia A., Shen, Xiaoli, Huang, Kai, Gilchuk, Pavlo, Flyak, Andrew I., Younan, Patrick, Alter, Galit, Crowe, James E., Bukreyev, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107261/
https://ncbi.nlm.nih.gov/pubmed/30138408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007204
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