Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap

Recent studies suggest that some monoclonal antibodies (mAbs) specific for ebolavirus glycoprotein (GP) can protect experimental animals against infections. Most mAbs isolated from ebolavirus survivors appeared to target the glycan cap or the stalk region of the viral GP, which is the envelope prote...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Ilinykh, Philipp A., Santos, Rodrigo I., Gunn, Bronwyn M., Kuzmina, Natalia A., Shen, Xiaoli, Huang, Kai, Gilchuk, Pavlo, Flyak, Andrew I., Younan, Patrick, Alter, Galit, Crowe, James E., Bukreyev, Alexander
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107261/
https://ncbi.nlm.nih.gov/pubmed/30138408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007204
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