Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap

Recent studies suggest that some monoclonal antibodies (mAbs) specific for ebolavirus glycoprotein (GP) can protect experimental animals against infections. Most mAbs isolated from ebolavirus survivors appeared to target the glycan cap or the stalk region of the viral GP, which is the envelope prote...

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Bibliografische gegevens
Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Ilinykh, Philipp A., Santos, Rodrigo I., Gunn, Bronwyn M., Kuzmina, Natalia A., Shen, Xiaoli, Huang, Kai, Gilchuk, Pavlo, Flyak, Andrew I., Younan, Patrick, Alter, Galit, Crowe, James E., Bukreyev, Alexander
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107261/
https://ncbi.nlm.nih.gov/pubmed/30138408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007204
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