Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine

Ebolaviruses Zaire (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) cause human disease with high case fatality rates. Experimental monovalent vaccines, which all utilize the sole envelope glycoprotein (GP), do not protect against heterologous ebolaviruses. Human parainfluenza virus type 3-vectored vacci...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Kimble, J. Brian, Malherbe, Delphine C., Meyer, Michelle, Gunn, Bronwyn M., Karim, Marcus M., Ilinykh, Philipp A., Iampietro, Mathieu, Mohamed, Khaled S., Negi, Surendra, Gilchuk, Pavlo, Huang, Kai, Wolf, Yuri I., Braun, Werner, Crowe, James E., Alter, Galit, Bukreyev, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364037/
https://ncbi.nlm.nih.gov/pubmed/30518655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01845-18
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