Biophysical and Proteomic Characterization Strategies for Cysteine Modifications in Ras GTPases

le Hobbs, G. Aaron, Gunawardena, Harsha P., Campbell, Sharon L.
Foilsithe 2014

RAS isoforms and mutations in cancer at a glance

le Hobbs, G. Aaron, Der, Channing J., Rossman, Kent L.
Foilsithe in J Cell Sci (2016)

Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy

le Bhaskar, Kiran, Hobbs, G. Aaron, Yen, Shu-Hui, Lee, Gloria
Foilsithe 2010

Redox Regulation of Ras and Rho GTPases: Mechanism and Function

le Mitchell, Lauren, Hobbs, G. Aaron, Aghajanian, Amir, Campbell, Sharon L.
Foilsithe 2013

Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function

le Hobbs, G Aaron, Gunawardena, Harsha P, Baker, Rachael, Campbell, Sharon L
Foilsithe 2013

Rho GTPases, oxidation, and cell redox control

le Hobbs, G Aaron, Zhou, Bingying, Cox, Adrienne D, Campbell, Sharon L
Foilsithe 2014

Glutathiolated Ras: Characterization and Implications for Ras Activation

le Hobbs, G. Aaron, Bonini, Marcelo G., Gunawardena, Harsha P., Chen, Xian, Campbell, Sharon L.
Foilsithe 2012

Redox regulation of Rac1 by thiol oxidation

le Hobbs, G. Aaron, Mitchell, Lauren E., Arrington, Megan E., Gunawardena, Harsha P., DeCristo, Molly J., Loeser, Richard F., Chen, Xian, Cox, Adrienne D., Campbell, Sharon L.
Foilsithe in Free Radic Biol Med (2014)

Copper is required for oncogenic BRAF signaling and tumorigenesis

le Brady, Donita C., Crowe, Matthew S., Turski, Michelle L., Hobbs, G. Aaron, Yao, Xiaojie, Chaikuad, Apirat, Knapp, Stefan, Xiao, Kunhong, Campbell, Sharon L., Thiele, Dennis J., Counter, Christopher M.
Foilsithe 2014

Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies

le Waters, Andrew M., Ozkan-Dagliyan, Irem, Vaseva, Angelina V., Fer, Nicole, Strathern, Leslie A., Hobbs, G. Aaron, Tessier-Cloutier, Basile, Gillette, William K., Bagni, Rachel, Whiteley, Gordon R., Hartley, James L., McCormick, Frank, Cox, Adrienne D., Houghton, Peter J., Huntsman, David G., Philips, Mark R., Der, Channing J.
Foilsithe in Sci Signal (2017)

Atypical KRAS(G12R) Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer

le Hobbs, G. Aaron, Baker, Nicole M., Miermont, Anne M., Thurman, Ryan D., Pierobon, Mariaelena, Tran, Timothy H., Anderson, Andrew O., Waters, Andrew M., Diehl, J. Nathaniel, Papke, Bjoern, Hodge, Richard G., Klomp, Jennifer E., Goodwin, Craig M., DeLiberty, Jonathan M., Wang, Junning, Ng, Raymond W. S., Gautam, Prson, Bryant, Kirsten L., Esposito, Dominic, Campbell, Sharon L., Petricoin, Emanuel F., Simanshu, Dhirendra K., Aguirre, Andrew J., Wolpin, Brian M., Wennerberg, Krister, Rudloff, Udo, Cox, Adrienne D., Der, Channing J.
Foilsithe in Cancer Discov (2019)

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

le Bryant, Kirsten L., Stalnecker, Clint A., Zeitouni, Daniel, Klomp, Jennifer E., Peng, Sen, Tikunov, Andrey P., Gunda, Venugopal, Pierobon, Mariaelena, Waters, Andrew M., George, Samuel D., Tomar, Garima, Papke, Björn, Hobbs, G. Aaron, Yan, Liang, Hayes, Tikvah K., Diehl, J. Nathaniel, Goode, Gennifer D., Chaika, Nina V., Wang, Yingxue, Zhang, Guo-Fang, Witkiewicz, Agnieszka K., Knudsen, Erik S., Petricoin, Emanuel F., Singh, Pankaj K., Macdonald, Jeffrey M., Tran, Nhan L., Lyssiotis, Costas A., Ying, Haoqiang, Kimmelman, Alec C., Cox, Adrienne D., Der, Channing J.
Foilsithe in Nat Med (2019)