Transcriptional Regulation of CYP2B6 Expression by Hepatocyte Nuclear Factor 3β in Human Liver Cells

av Li, Linhao, Li, Daochuan, Heyward, Scott, Wang, Hongbing
I publikationen PLoS One (2016)

Metformin Represses Drug-Induced Expression of CYP2B6 by Modulating the Constitutive Androstane Receptor Signaling

av Yang, Hui, Garzel, Brandy, Heyward, Scott, Moeller, Timothy, Shapiro, Paul, Wang, Hongbing
Publicerad 2014

High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis

av Mackowiak, Bryan, Li, Linhao, Lynch, Caitlin, Ziman, Andrew, Heyward, Scott, Xia, Menghang, Wang, Hongbing
I publikationen Biochem Pharmacol (2019)

Efficient Transduction by an Amphotropic Retrovirus Vector Is Dependent on High-Level Expression of the Cell Surface Virus Receptor

av Kurre, Peter, Kiem, Hans-Peter, Morris, Julia, Heyward, Scott, Battini, Jean-Luc, Miller, A. Dusty
Publicerad 1999

Activation of the Constitutive Androstane Receptor Inhibits Gluconeogenesis without Affecting Lipogenesis or Fatty Acid Synthesis in Human Hepatocytes

av Lynch, Caitlin, Pan, Yongmei, Li, Linhao, Heyward, Scott, Moeller, Timothy, Swaan, Peter W., Wang, Hongbing
Publicerad 2014

Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity

av Li, Xiaohai, Jeso, Valer, Heyward, Scott, Walker, Gregory S., Sharma, Raman, Micalizio, Glenn C., Cameron, Michael D.
Publicerad 2014

Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor

av Lynch, Caitlin, Zhao, Jinghua, Huang, Ruili, Xiao, Jingwei, Li, Linhao, Heyward, Scott, Xia, Menghang, Wang, Hongbing
I publikationen Sci Rep (2015)

Identification of Modulators That Activate the Constitutive Androstane Receptor From the Tox21 10K Compound Library

av Lynch, Caitlin, Mackowiak, Bryan, Huang, Ruili, Li, Linhao, Heyward, Scott, Sakamuru, Srilatha, Wang, Hongbing, Xia, Menghang
I publikationen Toxicol Sci (2019)

Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor

av Li, Linhao, Welch, Matthew A., Li, Zhihui, Mackowiak, Bryan, Heyward, Scott, Swaan, Peter W., Wang, Hongbing
I publikationen Mol Pharmacol (2019)

Activation of the constitutive androstane receptor increases the therapeutic index of CHOP in lymphoma treatment

av Hedrich, William D., Xiao, Jingwei, Heyward, Scott, Zhang, Yao, Zhang, Junran, Baer, Maria R., Hassan, Hazem E., Wang, Hongbing
I publikationen Mol Cancer Ther (2016)

A Targeted LC-MS/MS Proteomics-Based Strategy to Characterize In Vitro Models Used in Drug Metabolism and Transport Studies

av Xu, Meijuan, Saxena, Neha, Vrana, Marc, Zhang, Haeyoung, Kumar, Vineet, Billington, Sarah, Khojasteh, Cyrus, Heyward, Scott, Unadkat, Jashvant D., Prasad, Bhagwat
I publikationen Anal Chem (2018)

Molecular Basis of Metabolism-Mediated Conversion of PK11195 from an Antagonist to an Agonist of the Constitutive Androstane Receptor

av Mackowiak, Bryan, Li, Linhao, Welch, Matthew A., Li, Daochuan, Jones, Jace W., Heyward, Scott, Kane, Maureen A., Swaan, Peter W., Wang, Hongbing
I publikationen Mol Pharmacol (2017)

Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression

av Garzel, Brandy, Hu, Tao, Li, Linhao, Lu, Yuanfu, Heyward, Scott, Polli, James, Zhang, Lei, Huang, Shiew-Mei, Raufman, Jean-Pierre, Wang, Hongbing
I publikationen Pharm Res (2020)

Human constitutive androstane receptor agonist DL5016: a novel sensitizer for cyclophosphamide-based chemotherapies

av Liang, Dongdong, Li, Linhao, Lynch, Caitlin, Mackowiak, Bryan, Hedrich, William D., Ai, Yong, Yin, Yue, Heyward, Scott, Xia, Menghang, Wang, Hongbing, Xue, Fengtian
I publikationen Eur J Med Chem (2019)

SLC13A5 Is a Novel Transcriptional Target of the Pregnane X Receptor and Sensitizes Drug-Induced Steatosis in Human Liver

av Li, Linhao, Li, Haishan, Garzel, Brandy, Yang, Hui, Sueyoshi, Tatsuya, Li, Qing, Shu, Yan, Zhang, Junran, Hu, Bingfang, Heyward, Scott, Moeller, Timothy, Xie, Wen, Negishi, Masahiko, Wang, Hongbing
I publikationen Mol Pharmacol (2015)

Prospective Cohort Study of Mother-to-Infant Infection and Clearance of Hepatitis C in Rural Egyptian Villages

av Shebl, Fatma M., El-Kamary, Samer S., Saleh, Doa’a A., Abdel-Hamid, Mohamed, Mikhail, Nabiel, Allam, Alif, El-Arabi, Hanaa, Elhenawy, Ibrahim, El-Kafrawy, Sherif, El-Daly, Mai, Selim, Sahar, El-Wahab, Ayman Abd, Mostafa, Mohamed, Sharaf, Soraya, Hashem, Mohamed, Heyward, Scott, Stine, O. Colin, Magder, Laurence S., Stoszek, Sonia, Strickland, G. Thomas
Publicerad 2009