Transcriptional Regulation of CYP2B6 Expression by Hepatocyte Nuclear Factor 3β in Human Liver Cells

Por Li, Linhao, Li, Daochuan, Heyward, Scott, Wang, Hongbing
Publicado no PLoS One (2016)

Metformin Represses Drug-Induced Expression of CYP2B6 by Modulating the Constitutive Androstane Receptor Signaling

Por Yang, Hui, Garzel, Brandy, Heyward, Scott, Moeller, Timothy, Shapiro, Paul, Wang, Hongbing
Publicado em 2014

High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis

Por Mackowiak, Bryan, Li, Linhao, Lynch, Caitlin, Ziman, Andrew, Heyward, Scott, Xia, Menghang, Wang, Hongbing
Publicado no Biochem Pharmacol (2019)

Efficient Transduction by an Amphotropic Retrovirus Vector Is Dependent on High-Level Expression of the Cell Surface Virus Receptor

Por Kurre, Peter, Kiem, Hans-Peter, Morris, Julia, Heyward, Scott, Battini, Jean-Luc, Miller, A. Dusty
Publicado em 1999

Activation of the Constitutive Androstane Receptor Inhibits Gluconeogenesis without Affecting Lipogenesis or Fatty Acid Synthesis in Human Hepatocytes

Por Lynch, Caitlin, Pan, Yongmei, Li, Linhao, Heyward, Scott, Moeller, Timothy, Swaan, Peter W., Wang, Hongbing
Publicado em 2014

Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity

Por Li, Xiaohai, Jeso, Valer, Heyward, Scott, Walker, Gregory S., Sharma, Raman, Micalizio, Glenn C., Cameron, Michael D.
Publicado em 2014

Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor

Por Lynch, Caitlin, Zhao, Jinghua, Huang, Ruili, Xiao, Jingwei, Li, Linhao, Heyward, Scott, Xia, Menghang, Wang, Hongbing
Publicado no Sci Rep (2015)

Identification of Modulators That Activate the Constitutive Androstane Receptor From the Tox21 10K Compound Library

Por Lynch, Caitlin, Mackowiak, Bryan, Huang, Ruili, Li, Linhao, Heyward, Scott, Sakamuru, Srilatha, Wang, Hongbing, Xia, Menghang
Publicado no Toxicol Sci (2019)

Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor

Por Li, Linhao, Welch, Matthew A., Li, Zhihui, Mackowiak, Bryan, Heyward, Scott, Swaan, Peter W., Wang, Hongbing
Publicado no Mol Pharmacol (2019)

Activation of the constitutive androstane receptor increases the therapeutic index of CHOP in lymphoma treatment

Por Hedrich, William D., Xiao, Jingwei, Heyward, Scott, Zhang, Yao, Zhang, Junran, Baer, Maria R., Hassan, Hazem E., Wang, Hongbing
Publicado no Mol Cancer Ther (2016)

A Targeted LC-MS/MS Proteomics-Based Strategy to Characterize In Vitro Models Used in Drug Metabolism and Transport Studies

Por Xu, Meijuan, Saxena, Neha, Vrana, Marc, Zhang, Haeyoung, Kumar, Vineet, Billington, Sarah, Khojasteh, Cyrus, Heyward, Scott, Unadkat, Jashvant D., Prasad, Bhagwat
Publicado no Anal Chem (2018)

Molecular Basis of Metabolism-Mediated Conversion of PK11195 from an Antagonist to an Agonist of the Constitutive Androstane Receptor

Por Mackowiak, Bryan, Li, Linhao, Welch, Matthew A., Li, Daochuan, Jones, Jace W., Heyward, Scott, Kane, Maureen A., Swaan, Peter W., Wang, Hongbing
Publicado no Mol Pharmacol (2017)

Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression

Por Garzel, Brandy, Hu, Tao, Li, Linhao, Lu, Yuanfu, Heyward, Scott, Polli, James, Zhang, Lei, Huang, Shiew-Mei, Raufman, Jean-Pierre, Wang, Hongbing
Publicado no Pharm Res (2020)

Human constitutive androstane receptor agonist DL5016: a novel sensitizer for cyclophosphamide-based chemotherapies

Por Liang, Dongdong, Li, Linhao, Lynch, Caitlin, Mackowiak, Bryan, Hedrich, William D., Ai, Yong, Yin, Yue, Heyward, Scott, Xia, Menghang, Wang, Hongbing, Xue, Fengtian
Publicado no Eur J Med Chem (2019)

SLC13A5 Is a Novel Transcriptional Target of the Pregnane X Receptor and Sensitizes Drug-Induced Steatosis in Human Liver

Por Li, Linhao, Li, Haishan, Garzel, Brandy, Yang, Hui, Sueyoshi, Tatsuya, Li, Qing, Shu, Yan, Zhang, Junran, Hu, Bingfang, Heyward, Scott, Moeller, Timothy, Xie, Wen, Negishi, Masahiko, Wang, Hongbing
Publicado no Mol Pharmacol (2015)

Prospective Cohort Study of Mother-to-Infant Infection and Clearance of Hepatitis C in Rural Egyptian Villages

Por Shebl, Fatma M., El-Kamary, Samer S., Saleh, Doa’a A., Abdel-Hamid, Mohamed, Mikhail, Nabiel, Allam, Alif, El-Arabi, Hanaa, Elhenawy, Ibrahim, El-Kafrawy, Sherif, El-Daly, Mai, Selim, Sahar, El-Wahab, Ayman Abd, Mostafa, Mohamed, Sharaf, Soraya, Hashem, Mohamed, Heyward, Scott, Stine, O. Colin, Magder, Laurence S., Stoszek, Sonia, Strickland, G. Thomas
Publicado em 2009