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Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression
PURPOSE: The bile salt export pump (BSEP), a key player in hepatic bile acid clearance, has been the center of research on drug-induced cholestasis. However, such studies focus primarily on the direct inhibition of BSEP, often overlooking the potential impact of transcriptional repression. This work...
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| Pubblicato in: | Pharm Res |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7357855/ https://ncbi.nlm.nih.gov/pubmed/31907698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-019-2753-x |
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