A Targeted LC-MS/MS Proteomics-Based Strategy to Characterize In Vitro Models Used in Drug Metabolism and Transport Studies

Subcellular fractionation of tissue homogenate provides enriched in vitro models (e.g., microsomes, cytosol, or membranes), which are routinely used in the drug metabolism or transporter activity and protein abundance studies. However, batch-to-batch or inter-laboratory variability in the recovery,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Anal Chem
Hauptverfasser: Xu, Meijuan, Saxena, Neha, Vrana, Marc, Zhang, Haeyoung, Kumar, Vineet, Billington, Sarah, Khojasteh, Cyrus, Heyward, Scott, Unadkat, Jashvant D., Prasad, Bhagwat
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414395/
https://ncbi.nlm.nih.gov/pubmed/30204418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b01913
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge