Transcriptional Regulation of CYP2B6 Expression by Hepatocyte Nuclear Factor 3β in Human Liver Cells

מאת Li, Linhao, Li, Daochuan, Heyward, Scott, Wang, Hongbing
הוצא לאור ב PLoS One (2016)

Metformin Represses Drug-Induced Expression of CYP2B6 by Modulating the Constitutive Androstane Receptor Signaling

מאת Yang, Hui, Garzel, Brandy, Heyward, Scott, Moeller, Timothy, Shapiro, Paul, Wang, Hongbing
יצא לאור 2014

High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis

מאת Mackowiak, Bryan, Li, Linhao, Lynch, Caitlin, Ziman, Andrew, Heyward, Scott, Xia, Menghang, Wang, Hongbing
הוצא לאור ב Biochem Pharmacol (2019)

Efficient Transduction by an Amphotropic Retrovirus Vector Is Dependent on High-Level Expression of the Cell Surface Virus Receptor

מאת Kurre, Peter, Kiem, Hans-Peter, Morris, Julia, Heyward, Scott, Battini, Jean-Luc, Miller, A. Dusty
יצא לאור 1999

Activation of the Constitutive Androstane Receptor Inhibits Gluconeogenesis without Affecting Lipogenesis or Fatty Acid Synthesis in Human Hepatocytes

מאת Lynch, Caitlin, Pan, Yongmei, Li, Linhao, Heyward, Scott, Moeller, Timothy, Swaan, Peter W., Wang, Hongbing
יצא לאור 2014

Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity

מאת Li, Xiaohai, Jeso, Valer, Heyward, Scott, Walker, Gregory S., Sharma, Raman, Micalizio, Glenn C., Cameron, Michael D.
יצא לאור 2014

Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor

מאת Lynch, Caitlin, Zhao, Jinghua, Huang, Ruili, Xiao, Jingwei, Li, Linhao, Heyward, Scott, Xia, Menghang, Wang, Hongbing
הוצא לאור ב Sci Rep (2015)

Identification of Modulators That Activate the Constitutive Androstane Receptor From the Tox21 10K Compound Library

מאת Lynch, Caitlin, Mackowiak, Bryan, Huang, Ruili, Li, Linhao, Heyward, Scott, Sakamuru, Srilatha, Wang, Hongbing, Xia, Menghang
הוצא לאור ב Toxicol Sci (2019)

Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor

מאת Li, Linhao, Welch, Matthew A., Li, Zhihui, Mackowiak, Bryan, Heyward, Scott, Swaan, Peter W., Wang, Hongbing
הוצא לאור ב Mol Pharmacol (2019)

Activation of the constitutive androstane receptor increases the therapeutic index of CHOP in lymphoma treatment

מאת Hedrich, William D., Xiao, Jingwei, Heyward, Scott, Zhang, Yao, Zhang, Junran, Baer, Maria R., Hassan, Hazem E., Wang, Hongbing
הוצא לאור ב Mol Cancer Ther (2016)

A Targeted LC-MS/MS Proteomics-Based Strategy to Characterize In Vitro Models Used in Drug Metabolism and Transport Studies

מאת Xu, Meijuan, Saxena, Neha, Vrana, Marc, Zhang, Haeyoung, Kumar, Vineet, Billington, Sarah, Khojasteh, Cyrus, Heyward, Scott, Unadkat, Jashvant D., Prasad, Bhagwat
הוצא לאור ב Anal Chem (2018)

Molecular Basis of Metabolism-Mediated Conversion of PK11195 from an Antagonist to an Agonist of the Constitutive Androstane Receptor

מאת Mackowiak, Bryan, Li, Linhao, Welch, Matthew A., Li, Daochuan, Jones, Jace W., Heyward, Scott, Kane, Maureen A., Swaan, Peter W., Wang, Hongbing
הוצא לאור ב Mol Pharmacol (2017)

Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression

מאת Garzel, Brandy, Hu, Tao, Li, Linhao, Lu, Yuanfu, Heyward, Scott, Polli, James, Zhang, Lei, Huang, Shiew-Mei, Raufman, Jean-Pierre, Wang, Hongbing
הוצא לאור ב Pharm Res (2020)

Human constitutive androstane receptor agonist DL5016: a novel sensitizer for cyclophosphamide-based chemotherapies

מאת Liang, Dongdong, Li, Linhao, Lynch, Caitlin, Mackowiak, Bryan, Hedrich, William D., Ai, Yong, Yin, Yue, Heyward, Scott, Xia, Menghang, Wang, Hongbing, Xue, Fengtian
הוצא לאור ב Eur J Med Chem (2019)

SLC13A5 Is a Novel Transcriptional Target of the Pregnane X Receptor and Sensitizes Drug-Induced Steatosis in Human Liver

מאת Li, Linhao, Li, Haishan, Garzel, Brandy, Yang, Hui, Sueyoshi, Tatsuya, Li, Qing, Shu, Yan, Zhang, Junran, Hu, Bingfang, Heyward, Scott, Moeller, Timothy, Xie, Wen, Negishi, Masahiko, Wang, Hongbing
הוצא לאור ב Mol Pharmacol (2015)

Prospective Cohort Study of Mother-to-Infant Infection and Clearance of Hepatitis C in Rural Egyptian Villages

מאת Shebl, Fatma M., El-Kamary, Samer S., Saleh, Doa’a A., Abdel-Hamid, Mohamed, Mikhail, Nabiel, Allam, Alif, El-Arabi, Hanaa, Elhenawy, Ibrahim, El-Kafrawy, Sherif, El-Daly, Mai, Selim, Sahar, El-Wahab, Ayman Abd, Mostafa, Mohamed, Sharaf, Soraya, Hashem, Mohamed, Heyward, Scott, Stine, O. Colin, Magder, Laurence S., Stoszek, Sonia, Strickland, G. Thomas
יצא לאור 2009