Transcriptional Regulation of CYP2B6 Expression by Hepatocyte Nuclear Factor 3β in Human Liver Cells

par Li, Linhao, Li, Daochuan, Heyward, Scott, Wang, Hongbing
Publié dans PLoS One (2016)

Metformin Represses Drug-Induced Expression of CYP2B6 by Modulating the Constitutive Androstane Receptor Signaling

par Yang, Hui, Garzel, Brandy, Heyward, Scott, Moeller, Timothy, Shapiro, Paul, Wang, Hongbing
Publié 2014

High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis

par Mackowiak, Bryan, Li, Linhao, Lynch, Caitlin, Ziman, Andrew, Heyward, Scott, Xia, Menghang, Wang, Hongbing
Publié dans Biochem Pharmacol (2019)

Efficient Transduction by an Amphotropic Retrovirus Vector Is Dependent on High-Level Expression of the Cell Surface Virus Receptor

par Kurre, Peter, Kiem, Hans-Peter, Morris, Julia, Heyward, Scott, Battini, Jean-Luc, Miller, A. Dusty
Publié 1999

Activation of the Constitutive Androstane Receptor Inhibits Gluconeogenesis without Affecting Lipogenesis or Fatty Acid Synthesis in Human Hepatocytes

par Lynch, Caitlin, Pan, Yongmei, Li, Linhao, Heyward, Scott, Moeller, Timothy, Swaan, Peter W., Wang, Hongbing
Publié 2014

Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity

par Li, Xiaohai, Jeso, Valer, Heyward, Scott, Walker, Gregory S., Sharma, Raman, Micalizio, Glenn C., Cameron, Michael D.
Publié 2014

Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor

par Lynch, Caitlin, Zhao, Jinghua, Huang, Ruili, Xiao, Jingwei, Li, Linhao, Heyward, Scott, Xia, Menghang, Wang, Hongbing
Publié dans Sci Rep (2015)

Identification of Modulators That Activate the Constitutive Androstane Receptor From the Tox21 10K Compound Library

par Lynch, Caitlin, Mackowiak, Bryan, Huang, Ruili, Li, Linhao, Heyward, Scott, Sakamuru, Srilatha, Wang, Hongbing, Xia, Menghang
Publié dans Toxicol Sci (2019)

Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor

par Li, Linhao, Welch, Matthew A., Li, Zhihui, Mackowiak, Bryan, Heyward, Scott, Swaan, Peter W., Wang, Hongbing
Publié dans Mol Pharmacol (2019)

Activation of the constitutive androstane receptor increases the therapeutic index of CHOP in lymphoma treatment

par Hedrich, William D., Xiao, Jingwei, Heyward, Scott, Zhang, Yao, Zhang, Junran, Baer, Maria R., Hassan, Hazem E., Wang, Hongbing
Publié dans Mol Cancer Ther (2016)

A Targeted LC-MS/MS Proteomics-Based Strategy to Characterize In Vitro Models Used in Drug Metabolism and Transport Studies

par Xu, Meijuan, Saxena, Neha, Vrana, Marc, Zhang, Haeyoung, Kumar, Vineet, Billington, Sarah, Khojasteh, Cyrus, Heyward, Scott, Unadkat, Jashvant D., Prasad, Bhagwat
Publié dans Anal Chem (2018)

Molecular Basis of Metabolism-Mediated Conversion of PK11195 from an Antagonist to an Agonist of the Constitutive Androstane Receptor

par Mackowiak, Bryan, Li, Linhao, Welch, Matthew A., Li, Daochuan, Jones, Jace W., Heyward, Scott, Kane, Maureen A., Swaan, Peter W., Wang, Hongbing
Publié dans Mol Pharmacol (2017)

Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression

par Garzel, Brandy, Hu, Tao, Li, Linhao, Lu, Yuanfu, Heyward, Scott, Polli, James, Zhang, Lei, Huang, Shiew-Mei, Raufman, Jean-Pierre, Wang, Hongbing
Publié dans Pharm Res (2020)

Human constitutive androstane receptor agonist DL5016: a novel sensitizer for cyclophosphamide-based chemotherapies

par Liang, Dongdong, Li, Linhao, Lynch, Caitlin, Mackowiak, Bryan, Hedrich, William D., Ai, Yong, Yin, Yue, Heyward, Scott, Xia, Menghang, Wang, Hongbing, Xue, Fengtian
Publié dans Eur J Med Chem (2019)

SLC13A5 Is a Novel Transcriptional Target of the Pregnane X Receptor and Sensitizes Drug-Induced Steatosis in Human Liver

par Li, Linhao, Li, Haishan, Garzel, Brandy, Yang, Hui, Sueyoshi, Tatsuya, Li, Qing, Shu, Yan, Zhang, Junran, Hu, Bingfang, Heyward, Scott, Moeller, Timothy, Xie, Wen, Negishi, Masahiko, Wang, Hongbing
Publié dans Mol Pharmacol (2015)

Prospective Cohort Study of Mother-to-Infant Infection and Clearance of Hepatitis C in Rural Egyptian Villages

par Shebl, Fatma M., El-Kamary, Samer S., Saleh, Doa’a A., Abdel-Hamid, Mohamed, Mikhail, Nabiel, Allam, Alif, El-Arabi, Hanaa, Elhenawy, Ibrahim, El-Kafrawy, Sherif, El-Daly, Mai, Selim, Sahar, El-Wahab, Ayman Abd, Mostafa, Mohamed, Sharaf, Soraya, Hashem, Mohamed, Heyward, Scott, Stine, O. Colin, Magder, Laurence S., Stoszek, Sonia, Strickland, G. Thomas
Publié 2009