The Mechanism of Action of (–)-Lomaiviticin A

Por Herzon, Seth B.
Publicado no Acc Chem Res (2017)

Scope and Limitations of 2-Deoxy- and 2,6-Dideoxyglycosyl Bromides as Donors for the Synthesis of β-2-Deoxy- and β-2,6-Dideoxyglycosides

Por Kaneko, Miho, Herzon, Seth B.
Publicado em 2014

Mechanism of Nucleophilic Activation of (−)-Lomaiviticin A

Por Xue, Mengzhao, Herzon, Seth B.
Publicado no J Am Chem Soc (2016)

Non-classical selectivities in the reduction of alkenes by cobalt-mediated hydrogen atom transfer

Por Ma, Xiaoshen, Herzon, Seth B.
Publicado no Chem Sci (2015)

Direct, Catalytic Hydroaminoalkylation of Unactivated Olefins with N-Alkyl Arylamines

Por Herzon, Seth B., Hartwig, John F.
Publicado em 2007

Hydroaminoalkylation of Unactivated Olefins with Dialkylamines

Por Herzon, Seth B., Hartwig, John F.
Publicado no J Am Chem Soc (2008)

Synergistic potentiation of (−)-lomaiviticin A cytotoxicity by the ATR inhibitor VE-821

Por Colis, Laureen C., Herzon, Seth B.
Publicado no Bioorg Med Chem Lett (2016)

Multigram Synthesis of 1-O-Acetyl-3-O-(4-methoxybenzyl)-4-N-(9-fluorenylmethoxycarbonyl)-4-N-methyl-L-pyrrolosamine

Por Burk, Matthew, Wilson, Nolan, Herzon, Seth B.
Publicado no Tetrahedron Lett (2014)

A concise synthesis of (+)-batzelladine B from simple pyrrole-based starting materials

Por Parr, Brendan T., Economou, Christos, Herzon, Seth B.
Publicado no Nature (2015)

The pharmacology and therapeutic potential of (−)-huperzine A

Por Tun, Maung Kyaw Moe, Herzon, Seth B
Publicado no J Exp Pharmacol (2012)

Direct Synthesis of β-N-Glycosides by the Reductive Glycosylation of Azides with Protected and Native Carbohydrate Donors()

Por Zheng, Jianbin, Urkalan, Kaveri Balan, Herzon, Seth B.
Publicado no Angew Chem Int Ed Engl (2013)

Evidence for the Rapid Conversion of Stephacidin B into the Electrophilic Monomer Avrainvillamide in Cell Culture

Por Wulff, Jeremy E., Herzon, Seth B., Siegrist, Romain, Myers, Andrew G.
Publicado em 2007

Analysis of Diazofluorene DNA Binding and Damaging Activity. DNA Cleavage by a Synthetic Monomeric Diazofluorene

Por Woo, Christina M., Ranjan, Nihar, Arya, Dev P., Herzon, Seth B.
Publicado em 2014

Structural basis for DNA cleavage by the potent antiproliferative agent (–)-lomaiviticin A

Por Woo, Christina M., Li, Zhenwu, Paulson, Eric K., Herzon, Seth B.
Publicado no Proc Natl Acad Sci U S A (2016)

11-Step Enantioselective Synthesis of (−)-Lomaiviticin Aglycon

Por Herzon, Seth B., Lu, Liang, Woo, Christina M., Gholap, Shivajirao L.
Publicado no J Am Chem Soc (2011)

Convergent and Modular Synthesis of Candidate Precolibactins. Structural Revision of Precolibactin A

Por Healy, Alan R., Vizcaino, Maria I., Crawford, Jason M., Herzon, Seth B.
Publicado no J Am Chem Soc (2016)

Mechanism of Action Studies of Lomaiviticin A and the Monomeric Lomaiviticin Aglycon. Selective and Potent Activity Toward DNA Double-Strand Break Repair-Deficient Cell Lines

Por Colis, Laureen C., Hegan, Denise C., Kaneko, Miho, Glazer, Peter M., Herzon, Seth B.
Publicado no J Am Chem Soc (2015)

A Mechanistic Model for Colibactin-Induced Genotoxicity

Por Healy, Alan R., Nikolayevskiy, Herman, Patel, Jaymin R., Crawford, Jason M., Herzon, Seth B.
Publicado no J Am Chem Soc (2016)

A complex stereochemical relay approach to the antimalarial alkaloid ocimicide A(1). Evidence for a structural revision

Por Nikolayevskiy, Herman, Moe Tun, Maung Kyaw, Rablen, Paul R., Ben Mamoun, Choukri, Herzon, Seth B.
Publicado no Chem Sci (2017)

Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis

Por Trautman, Eric P., Healy, Alan R., Shine, Emilee E., Herzon, Seth B., Crawford, Jason M.
Publicado no J Am Chem Soc (2017)