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A Mechanistic Model for Colibactin-Induced Genotoxicity
Precolibactins and colibactins represent a family of natural products that are encoded by the clb gene cluster and are produced by certain commensal, extraintestinal, and probiotic E. coli. clb(+) E. coli induce megalocytosis and DNA double-strand breaks in eukaryotic cells, but paradoxically, this...
Enregistré dans:
| Publié dans: | J Am Chem Soc |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5359767/ https://ncbi.nlm.nih.gov/pubmed/27934011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10354 |
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