Caricamento...

Model Colibactins Exhibit Human Cell Genotoxicity in the Absence of Host Bacteria

Colibactins are genotoxic secondary metabolites produced in select Enterobacteriaceae, which induce downstream DNA double-strand breaks (DSBs) in human cell lines and are thought to promote the formation of colorectal tumors. Although key structural and functional features of colibactins have been e...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:ACS Chem Biol
Autori principali: Shine, Emilee E., Xue, Mengzhao, Patel, Jaymin R., Healy, Alan R., Surovtseva, Yulia V., Herzon, Seth B., Crawford, Jason M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001666/
https://ncbi.nlm.nih.gov/pubmed/30403848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00714
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !