Cisplatin–DNA adducts inhibit translocation of the Ku subunits of DNA-PK

di Turchi, John J., Henkels, Karen M., Zhou, Yun
Pubblicazione 2000

INCREASED CELL GROWTH DUE TO A NEW LIPASE-GEF (PHOSPHOLIPASE D2) FASTLY ACTING ON RAS

di Henkels, Karen M., Mahankali, Madhu, Gomez-Cambronero, Julian
Pubblicazione 2012

A GEF-to-phospholipase molecular switch caused by phosphatidic acid, Rac and JAK tyrosine kinase that explains leukocyte cell migration

di Mahankali, Madhu, Henkels, Karen M., Gomez-Cambronero, Julian
Pubblicazione 2013

PLD-Specific Small-Molecule Inhibitors Decrease Tumor-Associated Macrophages and Neutrophils Infiltration in Breast Tumors and Lung and Liver Metastases

di Henkels, Karen M., Muppani, Naveen Reddy, Gomez-Cambronero, Julian
Pubblicato in PLoS One (2016)

Blocking K-Ras Interaction With the Plasma Membrane Is a Tractable Therapeutic Approach to Inhibit Oncogenic K-Ras Activity

di Henkels, Karen M., Rehl, Kristen M., Cho, Kwang-jin
Pubblicato in Front Mol Biosci (2021)

Identification of the Catalytic Site of Phospholipase D2 (PLD2) Newly Described Guanine Nucleotide Exchange Factor Activity

di Mahankali, Madhu, Henkels, Karen M., Alter, Gerald, Gomez-Cambronero, Julian
Pubblicazione 2012

A New Signaling Pathway (JAK-Fes-phospholipase D) That Is Enhanced in Highly Proliferative Breast Cancer Cells

di Ye, Qing, Kantonen, Samuel, Henkels, Karen M., Gomez-Cambronero, Julian
Pubblicazione 2013

The Molecular Basis of Leukocyte Adhesion Involving Phosphatidic Acid and Phospholipase D

di Speranza, Francis, Mahankali, Madhu, Henkels, Karen M., Gomez-Cambronero, Julian
Pubblicazione 2014

A non-mitotic role for Aurora kinase A as a direct activator of cell migration upon interaction with PLD, FAK and Src

di Mahankali, Madhu, Henkels, Karen M., Speranza, Francis, Gomez-Cambronero, Julian
Pubblicato in J Cell Sci (2015)

Cisplatin sensitizes cancer cells to ionizing radiation via inhibition of non-homologous end joining

di Boeckman, Heather J., Trego, Kelly S., Henkels, Karen M., Turchi, John J.
Pubblicazione 2005

A Comprehensive Model That Explains the Regulation of Phospholipase D2 Activity by Phosphorylation-Dephosphorylation

di Henkels, Karen M., Peng, Hong-Juan, Frondorf, Kathleen, Gomez-Cambronero, Julian
Pubblicazione 2010

Phosphatidic Acid Is a Leukocyte Chemoattractant That Acts through S6 Kinase Signaling

di Frondorf, Kathleen, Henkels, Karen M., Frohman, Michael A., Gomez-Cambronero, Julian
Pubblicazione 2010

S6K is a morphogenic protein with a mechanism involving Filamin-A phosphorylation and phosphatidic acid binding

di Henkels, Karen M., Mallets, Elizabeth R., Dennis, Patrick B., Gomez-Cambronero, Julian
Pubblicato in FASEB J (2015)

Phosphatidic Acid Increases Epidermal Growth Factor Receptor Expression by Stabilizing mRNA Decay and by Inhibiting Lysosomal and Proteasomal Degradation of the Internalized Recept...

di Hatton, Nathaniel, Lintz, Erin, Mahankali, Madhu, Henkels, Karen M., Gomez-Cambronero, Julian
Pubblicato in Mol Cell Biol (2015)

The Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling, in response to EGF

di Di Fulvio, Mauricio, Frondorf, Kathleen, Henkels, Karen M., Lehman, Nicholas, Gomez-Cambronero, Julian
Pubblicazione 2007

Cell Invasion of highly metastatic MTLn3 cancer cells is dependent on Phospholipase D2 (PLD2) and Janus Kinase 3 (JAK3)

di Henkels, Karen M., Farkaly, Terry, Mahankali, Madhu, Segall, Jeffrey E., Gomez-Cambronero, Julian
Pubblicazione 2011

PLD2 has both enzymatic and cell proliferation-inducing capabilities, that are differentially regulated by phosphorylation and dephosphorylation

di Henkels, Karen M., Short, Stephen, Peng, Hong-Juan, Fulvio, Mauricio Di, Gomez-Cambronero, Julian
Pubblicazione 2009

Evidence for Two CRIB Domains in Phospholipase D2 (PLD2) That the Enzyme Uses to Specifically Bind to the Small GTPase Rac2

di Peng, Hong-Juan, Henkels, Karen M., Mahankali, Madhu, Dinauer, Mary C., Gomez-Cambronero, Julian
Pubblicazione 2011

Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2

di Mahankali, Madhu, Peng, Hong-Juan, Henkels, Karen M., Dinauer, Mary C., Gomez-Cambronero, Julian
Pubblicazione 2011

PHOSPHOLIPASE D (PLD) DRIVES CELL INVASION, TUMOR GROWTH AND METASTASIS IN A HUMAN BREAST CANCER XENOGRAPH MODEL

di Henkels, Karen M., Boivin, Gregory P., Dudley, Emily S., Berberich, Steven J., Gomez-Cambronero, Julian
Pubblicazione 2013