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Cisplatin sensitizes cancer cells to ionizing radiation via inhibition of non-homologous end joining

The combination of cisplatin and ionizing radiation treatment represents a common modality for treating a variety of cancers. These two agents provide considerable synergy during treatment although the mechanism of this synergy remains largely undefined. We have investigated the mechanism of cisplat...

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Detalhes bibliográficos
Main Authors: Boeckman, Heather J., Trego, Kelly S., Henkels, Karen M., Turchi, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432110/
https://ncbi.nlm.nih.gov/pubmed/15886299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-04-0032
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